PMID: 8600069Jul 1, 1995Paper

Surface epithelial changes in endometrial adenocarcinoma: diagnostic pitfalls in curettage specimens

International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists
S M JacquesW D Lawrence

Abstract

A total of 161 uteri removed for endometrial cancer were studied in order to characterize the histopathologic features of the endometrial surface epithelium. Of these, 116 had endometrioid endometrial adenocarcinoma, and 45 had other endometrial cancers. A total of 57 (49%) of the endometrioid endometrial adenocarcinomas showed the following surface epithelial changes: seven had a conspicuous microglandular pattern simulating cervical microglandular hyperplasia; 17 had syncytial aggregates of relatively bland-appearing eosinophilic cells, frequently with papillary or squamoid differentiation simulating papillary syncytial change or other endometrial epithelial metaplasias; and 33 had mixed patterns. The surface epithelial changes varied in extent from rare foci to extensive surface replacement and were largely confined to FIGO grade I and II tumors. Cytologic atypicality varied from mild to moderate and was consistently less than that of the underlying carcinoma. Similar changes were present in some of the prior curettings; in some scanty curettings an unequivocal diagnosis of carcinoma was not possible. Consequently, further clinical investigation is indicated if these changes are present in scanty curettings from postmenopaus...Continue Reading

Citations

Jun 17, 2003·Annals of Diagnostic Pathology·Michal ZamecnikVaclav Opatrny
Oct 9, 2002·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Michal Zamecnik
Feb 2, 2013·Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B·Mai HeCynthia Jackson
Aug 30, 2008·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Sejal S Shah, Michael T Mazur
Aug 22, 2009·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·M Ruhul QuddusW Dwayne Lawrence
Dec 5, 2014·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Colin J R Stewart, Maxine L Crook
Jul 29, 2006·Journal of Clinical Pathology·W G McCluggage
Nov 15, 2003·International Journal of Surgical Pathology·Russell Vang, Fattaneh A Tavassoli
Sep 6, 2000·Histopathology·W G McCluggage, M Perenyei
Apr 21, 2004·Advances in Anatomic Pathology·W Glenn McCluggage
Aug 11, 2006·Diagnostic Cytopathology·Keiko ShimizuMasami Sakurai
Jan 8, 2019·Cytopathology : Official Journal of the British Society for Clinical Cytology·Yoshiaki NorimatsuTadao K Kobayashi
Mar 29, 2019·International Journal of Surgical Pathology·Jonathan WawireM Ruhul Quddus
Feb 28, 2015·The American Journal of Surgical Pathology·Jennifer Taylor, W Glenn McCluggage
Sep 27, 2003·Cytopathology : Official Journal of the British Society for Clinical Cytology·M Pajtler, M Mrcela
Dec 20, 2019·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Gozde KirW Glenn McCluggage
Mar 4, 2010·Archives of Pathology & Laboratory Medicine·Fabiola Medeiros, Debra A Bell
Mar 17, 2007·Pathology·W Glenn McCluggage

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