Surface-Initiated Poly(oligo(2-alkyl-2-oxazoline)methacrylate) Brushes

Langmuir : the ACS Journal of Surfaces and Colloids
Pei TangJulien E Gautrot

Abstract

Polymer brushes are particularly performant antifouling coatings, owing to their high grafting density that prevents unwanted biomacromolecules to diffuse through the coating and adhere to the underlying substrate. In addition to this structural feature, polymer brushes require a relatively high level of hydrophilicity and a globally neutral structure to display ultrahigh protein resistance. Poly(2-alkyl-2-oxaolines) are attractive building blocks for such coatings as they can display relatively high hydrophilicity, owing to their amide repeat units, but can also be side-chain and end-chain functionalized relatively readily. However, poly(2-alkyl-2-oxazolines) have not yet been introduced through a radical-mediated grafting from polymer brush structure that would confer the high level of grafting density that is the hallmark of highly protein resistant brushes. Here, we present the formation of a series of poly(oligo(2-alkyl-2-oxazoline)methacrylate) brushes generated via a grafting from approach, via atom transfer radical polymerization. We characterize the chemical structure of the resulting coatings via ellipsometry, Fourier-transform infrared spectroscopy, and X-ray photoelectron spectroscopy. We show that allyl end groups ...Continue Reading

References

Jan 5, 2002·Journal of Controlled Release : Official Journal of the Controlled Release Society·Kristi S AnsethChristopher N Bowman
Apr 8, 2004·Developmental Cell·Rowena McBeathChristopher S Chen
May 10, 2005·Biomacromolecules·Stefano TuguluHarm-Anton Klok
Jan 9, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Rupert KonradiMarcus Textor
May 5, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·C Rodriguez EmmeneggerA Bologna Alles
Jul 9, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Wei YangShaoyi Jiang
Sep 22, 2009·Angewandte Chemie·Richard Hoogenboom
Feb 19, 2010·Angewandte Chemie·Charles E Hoyle, Christopher N Bowman
Nov 23, 2010·The Journal of Physical Chemistry. B·Qing ShaoShaoyi Jiang
Mar 17, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Chao ZhaoJie Zheng
Apr 2, 2011·Bioconjugate Chemistry·Tacey X ViegasFrancesco M Veronese
May 20, 2011·Biomacromolecules·Kristian KempeUlrich S Schubert
Jun 7, 2011·Macromolecular Rapid Communications·Cesar Rodriguez-EmmeneggerWilhelm T S Huck
Sep 22, 2011·Biomacromolecules·Gesine GunkelWilhelm T S Huck
Jan 20, 2012·Macromolecular Rapid Communications·Verena SchenkFrank Wiesbrock
Feb 14, 2012·ACS Applied Materials & Interfaces·Mukesh AgrawalManfred Stamm
Apr 20, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Jiang WuYung Chang
May 23, 2012·Macromolecular Bioscience·Ning ZhangRainer Jordan
Aug 14, 2012·Macromolecular Rapid Communications·Tim R DargavilleRichard Hoogenboom
Sep 22, 2012·Macromolecular Rapid Communications·Rupert KonradiMarcus Textor
Apr 11, 2013·Integrative Biology : Quantitative Biosciences From Nano to Macro·Khooi Y TanJulien E Gautrot
Jul 13, 2013·Biomacromolecules·Brooke L FarrugiaTim R Dargaville
Apr 10, 2014·Cell Adhesion & Migration·Tim R DargavilleRichard Hoogenboom
Aug 12, 2014·Biomacromolecules·Dawid KedrackiCorinne Nardin
Jan 10, 2016·Biointerphases·Annika KroningKarsten Hinrichs
Oct 25, 2016·Angewandte Chemie·Giulia MorgeseEdmondo M Benetti
Dec 29, 2017·Angewandte Chemie·Giulia MorgeseEdmondo M Benetti
Aug 14, 2014·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Lutz TauhardtUlrich S Schubert
Mar 7, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xiajun ZhengYanmei Wang

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Citations

May 28, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Sezer ÖzenlerUmit Hakan Yildiz
Nov 25, 2021·Biomacromolecules·Suebin ParkByeong-Su Kim

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