Surface Modification of Intraocular Lenses

Chinese Medical Journal
Qi HuangGuiqin Wang

Abstract

This paper aimed to review the current literature on the surface modification of intraocular lenses (IOLs). All articles about surface modification of IOLs published up to 2015 were identified through a literature search on both PubMed and ScienceDirect. The articles on the surface modification of IOLs were included, but those on design modification and surface coating were excluded. Technology of surface modification included plasma, ion beam, layer-by-layer self-assembly, ultraviolet radiation, and ozone. The main molecules introduced into IOLs surface were poly (ethylene glycol), polyhedral oligomeric silsesquioxane, 2-methacryloyloxyethyl phosphorylcholine, TiO 2 , heparin, F-heparin, titanium, titanium nitride, vinyl pyrrolidone, and inhibitors of cytokines. The surface modification either resulted in a more hydrophobic lens, a more hydrophilic lens, or a lens with a hydrophilic anterior and hydrophobic posterior surface. Advances in research regarding surface modification of IOLs had led to a better biocompatibility in both in vitro and animal experiments. The surface modification is an efficient, convenient, economic and promising method to improve the biocompatibility of IOLs.

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Citations

Apr 6, 2018·European Journal of Ophthalmology·Mahmoud Fathy RatebAhmed Hasan Eldoghaimy
Jan 24, 2018·Stem Cells International·Jia Tang, Takashi Saito
Sep 28, 2020·Veterinary Ophthalmology·Kourtney K DowlerElizabeth A Giuliano
Feb 13, 2020·Journal of Cataract and Refractive Surgery·Jeewan S TitiyalJyoti Rawat
Oct 17, 2020·Vestnik oftalmologii·Yu N YusefN Yu Shkolyarenko
Sep 12, 2020·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Dutta Debarun, James S Wolffsohn
Jan 26, 2021·Journal of Ophthalmology·Yingying HongYinghong Ji
Feb 4, 2021·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Melania OlivieriDario Rusciano
Apr 20, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xiaorong LanYunbing Wang
Apr 19, 2021·International Journal of Pharmaceutics·Ana TopeteAna Paula Serro
Feb 13, 2021·Journal of Cataract and Refractive Surgery·Julius HienertOliver Findl

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Methods Mentioned

BETA
electron spectroscopy

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