Surface morphology of macrophages in the regressing corpus luteum, as revealed by scanning electron microscopy

The Anatomical Record
L G Paavola, C O Boyd

Abstract

Activated macrophages phagocytize moribund luteal cells and thus play a central role in the postpartum regression of corpora lutea in guinea pigs (Paavola, '79). When viewed by transmission electron microscopy (TEM), these luteal macrophages exhibit many surface protrusions. To characterize more fully the nature and extent of these evaginations, as well as to gain further understanding of phagocytes in their natural surroundings, luteal macrophages were studied in situ by scanning electron microscopy of regressing corpora lutea. Correlated TEM was carried out to confirm the identity of the various cell types. Even in low power scanning electron micrographs, macrophages are consipicuous, and can be readily distinguished from luteal cells by their surface topography. Luteal cell surfaces bear low ridge-like folds and sparse microvilli. In contrast, macrophages characteristically exhibit highly developed surface projections, the most common of which are knob-like or clubbed processes of varying size and shape. Other distinctive surface modifications displayed by luteal macrophages include long, slender filopodia, and well developed pseudopodia. These processes generally have an uneven distribution over the cell; thus, luteal macro...Continue Reading

References

Apr 1, 1976·The Journal of Pathology·M N WaltersT A Robertson
Jun 1, 1977·Biology of Reproduction·J J PelusoE S Hafez
Jun 15, 1975·The Journal of Comparative Neurology·D J Allen, F N Low
May 15, 1975·The Journal of Comparative Neurology·D J Allen
Jun 1, 1975·The American Journal of Anatomy·P Motta, J Van Blerkom
May 1, 1976·The Journal of Cell Biology·G Albrecht-Buehler
Jun 1, 1976·The Journal of Comparative Neurology·J J Malloy, F N Low
Jun 1, 1976·Experimental and Molecular Pathology·J M Orenstein, E Shelton
Aug 1, 1974·Journal of Ultrastructure Research·P ParakkalJ M Hanifin
Feb 15, 1974·The Journal of Comparative Neurology·M W Cloyd, F N Low
Jan 1, 1972·Zeitschrift für Zellforschung und mikroskopische Anatomie·T FujitaT Murakami

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Citations

Feb 13, 2001·General and Comparative Endocrinology·F GaytánJ E Sánchez-Criado
Aug 23, 2008·Fertility and Sterility·Akihisa TakasakiHitoshi Okamura
Sep 13, 2011·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Ulf Alexander WenzelGer van Zandbergen

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