Surfactin and fengycin B extracted from Bacillus pumilus W-7 provide protection against potato late blight via distinct and synergistic mechanisms.

Applied Microbiology and Biotechnology
Youyou WangRuixue Chang

Abstract

Potato late blight caused by Phytophthora infestans is one of the most serious plant diseases worldwide. Cyclic lipopeptides (CLPs) extracted from Bacillus strains exhibit a promising effect in the biocontrol of a variety of phytopathogens. However, the specific inhibitory effects and underlying mechanisms of CLPs against P. infestans are poorly understood. In this study, we showed that Bacillus pumilus W-7 can inhibit the growth of P. infestans mycelium. Two metabolites from W-7, surfactin and fengycin B, were identified using MS/MS. Fengycin B inhibited mycelium growth by inducing mycelium deformations, oxidative damage, and mitochondrial dysfunction. Surfactin induced potato plant defense responses by increasing the expression of the biocontrol genes (pod, pal, and cat) and their enzyme activities (POD, PAL, and CAT). Also, surfactin and fengycin B could exhibit a synergistic inhibitory effect on P. infestans. Taken together, our findings indicate that B. pumilus W-7 and its CLPs are potential environmentally friendly and effective biocontrol agents for the preservation of potato crops. KEY POINTS: • Lipopeptides of surfactin and fengycin B are extracted from Bacillus pumilus W-7. • Fengycin B inhibits Phytophthora infestans...Continue Reading

References

Sep 18, 2002·Antimicrobial Agents and Chemotherapy·Daisuke KobayashiNaoki Watanabe
Feb 22, 2008·Trends in Microbiology·Marc Ongena, Philippe Jacques
Apr 1, 1948·Proceedings of the Society for Experimental Biology and Medicine·M LANDY, G H WARREN
Jul 12, 2013·PloS One·Muthuirulan PushpanathanJeyaprakash Rajendhran
Oct 15, 2013·International Journal of Medical Microbiology : IJMM·Tanja SchneiderHarald Gross
May 29, 2014·Medicinal Research Reviews·Stephen A Cochrane, John C Vederas
Jul 22, 2014·Molecular Plant Pathology·Giovanni FaraceStéphan Dorey
Jan 30, 2015·BioMed Research International·Khem Raj Meena, Shamsher S Kanwar
May 11, 2016·Journal of Basic Microbiology·Divya NairSudarslal Sadasivan Nair
Aug 16, 2016·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Sujata S JhaGeetha S J
Feb 25, 2017·Frontiers in Microbiology·Punniyakotti ParthipanAruliah Rajasekar
May 22, 2017·Environmental Science and Pollution Research International·Gabriela MihalacheFrançois Krier
Jul 8, 2017·Applied Microbiology and Biotechnology·Haobin ZhaoMingliang Jin
Jan 30, 2018·The Journal of Physical Chemistry. B·Sreyoshi SurAlan Grossfield

❮ Previous
Next ❯

Citations

Sep 2, 2020·Journal of Natural Products·Hui-Xiang YangJi-Kai Liu

❮ Previous
Next ❯

Methods Mentioned

BETA
optical microscopy
scanning electron microscopy
MDA

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.