Surgeon-Performed Ultrasonographic Evaluation and Predication for Large Thyroid Nodules-A Case-Control Study

Surgery
Oded CohenMoshe Yehuda

Abstract

The management of large thyroid nodules remains unclear. Ultrasonography is a central tool in the assessment of thyroid nodules, yet its role in risk stratification of large thyroid nodules has been studied only seldomly. The aim of this study was to determine the utility of ultrasonography in characterizing and risk-stratifying thyroid nodules ≥3.0 cm. We performed a retrospective, case-control study of all thyroid nodules aspirated between January 2010 and May 2014. Sonographic features of nodules ≥3.0 cm were compared with nodules <3.0 cm. All nodules were assessed by a single high-volume thyroid surgeon. Data collected included size (cm), texture, echogenicity, shape, calcifications, border, spongiform appearance, and vascularity. A total of 537 nodules were included in the study, with 137 nodules (25.5%) ≥3.0 cm comprising the study group, and 400 nodules (74.5%) as the control group. No differences were found between the 2 groups regarding age, sex, and risk factors. Nodules ≥3.0 cm were associated with an increased risk for malignancy (odds ratio 2.41 [1.08-5.38]). Microcalcifications (26.3% vs 17.5%, P = .039), hypoechogenicity (40.8% vs 23.4%, P < .001), and irregular borders (14.3% vs 3.6%, P = .001) were more prevale...Continue Reading

Citations

Oct 9, 2021·Annales d'endocrinologie·John Bukasa KakambaIulia Potorac

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.