Surgery for hypertrophic cardiomyopathy

Biophysics Reviews
James J WuPaul G Bannon

Abstract

Hypertrophic cardiomyopathy (HCM) is a genetically determined cardiac disease characterised by otherwise unexplained myocardial hypertrophy of the left ventricle, and may result in left ventricular outflow tract obstruction. It is the most common cause of sudden cardiac death in young adults due to arrhythmias. Septal myectomy is a surgical treatment for HCM with moderate to severe outflow tract obstruction, and is indicated for patients with severe symptoms refractory to medical therapy. The surgical approach involves obtaining access to the interventricular septum via transaortic, transapical or transmitral approaches, and excising a portion of the hypertrophied myocardium to relieve the outflow tract obstruction. Large, contemporary series from centres experienced in septal myectomy patients have demonstrated a low early mortality of <2 %, excellent long-term survival that matches the general population, and durable relief of symptoms.

References

Mar 1, 1991·Journal of the American College of Cardiology·C SeilerH P Krayenbuehl
Jul 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·B HericD M Cosgrove
Oct 1, 1995·Circulation·E D WigleW G Williams
Mar 1, 1996·The Journal of Thoracic and Cardiovascular Surgery·R C Robbins, E B Stinson
Dec 1, 1996·The Journal of Thoracic and Cardiovascular Surgery·D A TheodoroB J Anderson
May 22, 1998·The Annals of Thoracic Surgery·M H SchönbeckM I Turina
Dec 31, 1998·The Journal of Thoracic and Cardiovascular Surgery·M YacoubR Radley-Smith
Jul 13, 2000·The Annals of Thoracic Surgery·W H MerrillH W Bender
Mar 29, 2001·Journal of Molecular and Cellular Cardiology·A J Marian, R Roberts
Feb 19, 2002·Journal of the American College of Cardiology·Maria J ErikssonHarry Rakowski
Nov 26, 2002·The Journal of Thoracic and Cardiovascular Surgery·Alexandre Ciappina HuebSérgio Almeida de Oliveira
Jan 1, 1958·British Heart Journal·D TEARE
Feb 6, 2004·The Journal of Thoracic and Cardiovascular Surgery·Kenji MinakataGordon K Danielson
Mar 27, 2004·The New England Journal of Medicine·Rick A Nishimura, David R Holmes
Aug 2, 2005·Journal of the American College of Cardiology·Steve R OmmenRick A Nishimura
Aug 3, 2006·Journal of Interventional Cardiology·Mahboob AlamNasser Lakkis
Dec 25, 2007·The Annals of Thoracic Surgery·Nicholas G SmediraEugene H Blackstone
May 31, 2008·Expert Review of Cardiovascular Therapy·Morgan L Brown, Hartzell V Schaff
Jan 13, 2009·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Patrick AntounJeffrey A Breall
Feb 24, 2009·European Heart Journal·Mahboob AlamNasser M Lakkis
Jan 28, 2010·The Annals of Thoracic Surgery·Nihan KayalarSoon J Park
Jun 2, 2010·European Heart Journal·Paola MelaciniBarry J Maron
Oct 5, 2010·The Journal of Thoracic and Cardiovascular Surgery·Elena A AshikhminaMartin D Abel
Aug 24, 2011·World Journal of Cardiology·Syed Wamique YusufIyad N Daher
Apr 24, 2012·European Heart Journal·Attilio IacovoniPaolo Ferrazzi
Jun 13, 2012·Progress in Cardiovascular Diseases·João L CavalcanteHarry M Lever
Jun 13, 2012·Progress in Cardiovascular Diseases·Ronald E RossSandhya K Balaram
Jun 22, 2012·European Heart Journal·Roberto SpoladoreIacopo Olivotto
Jun 28, 2012·European Heart Journal·Joseph A Dearani
Jul 17, 2012·Journal of the American College of Cardiology·Barry J MaronChristopher Semsarian
Aug 10, 2012·Lancet·Barry J Maron, Martin S Maron
Oct 9, 2012·The Annals of Thoracic Surgery·Salah E AltarabshehMichael J Ackerman
Apr 30, 2013·Expert Review of Cardiovascular Therapy·Sameh M SaidHartzell V Schaff

❮ Previous
Next ❯

Citations

Oct 12, 2020·The Annals of Thoracic Surgery·Stijn VanstraelenAlaaddin Yilmaz
Sep 7, 2021·Asian Cardiovascular & Thoracic Annals·Michael SecoPaul G Bannon

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Anti-Arrhythmic Drug Therapies

Anti-arrhythmic drugs are used to prevent abnormal heart rhythms. These medications are used in conditions including, ventricular tachycardia, ventricular fibrillation and atrial fibrillation. Discover the latest research on anti-arrhythmic drug therapies here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.