PMID: 9553595Apr 29, 1998Paper

Surgery for severe COPD. Lung volume reduction and lung transplantation

Postgraduate Medicine
G M O'Brien, G J Criner

Abstract

A management strategy for patients with severe emphysema is shown in figure 2 on page 199. Although the reported physiologic improvements after LVRS are significantly less than those seen after lung transplantation, LVRS has the potential to improve functional performance in a larger number of patients because of wider availability. Moreover, it accomplishes these goals without the attendant risks associated with transplantation and immunosuppression. The efficacy of LVRS over standard medical therapy in influencing survival and favorably affecting physiologic variables at rest and during exercise remains to be elucidated in NETT. Lung transplantation should be reserved for those patients deemed unsuitable or too ill for LVRS. It is to be hoped that future developments in organ preservation techniques and immunosuppressive regimens will expand the donor pool and decrease the incidence of posttransplantation bronchiolitis.

References

Feb 1, 1989·The American Review of Respiratory Disease·J D CooperJ Maurer
Sep 1, 1989·The American Review of Respiratory Disease·N R Anthonisen
Jan 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·J D CooperC L Roper
Aug 1, 1994·American Journal of Respiratory and Critical Care Medicine·S M LevineC L Bryan
Apr 25, 1996·The New England Journal of Medicine·F C SciurbaR J Landreneau
Sep 1, 1996·The European Respiratory Journal·H TeschlerN Konietzko
Jan 1, 1997·American Journal of Respiratory and Critical Care Medicine·J O BendittR K Albert
Jun 1, 1997·American Journal of Respiratory and Critical Care Medicine·F J MartinezB R Celli
Jul 1, 1997·American Journal of Respiratory and Critical Care Medicine·C A KellerK S Naunheim

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Citations

Mar 29, 2000·The Annals of Thoracic Surgery·M BrennerA F Wilson
Jun 27, 2003·Journal of Cardiothoracic and Vascular Anesthesia·Katherine P Grichnik, Steven E Hill
Jan 25, 2002·Clinics in Podiatric Medicine and Surgery·Elizabeth A Brown, Stephen P Hoffmann
Apr 20, 2002·Transplantation·Giancarlo RoviaroMarco Maciocco

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