PMID: 7546807Jan 1, 1995Paper

Surgery in native valve endocarditis: indications, results and risk factors

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
A DodgeH Sadeghi

Abstract

Seventy-nine patients (mean age 49 years) underwent valve replacement or repair for active (58.2%) or healed (41.8%) native valve endocarditis between 1976 and 1992. The most common indication for surgery was congestive heart failure (73.4%), followed by multiple systemic emboli (21.5%). Emergency operation was necessary in 27.8% of the cases. Operative mortality was 3.8% (3 patients) and late mortality 15.1% (12 patients). Streptococci were the most common infecting agents (41.8%), followed by Staphylococcus aureus (11.4%). No organisms were isolated in 27 cases (34.2%). Follow-up spanned 379.8 patient-years with a maximum of 15.8 years. Fifteen late valve-related events (periprosthetic leak, recurrent endocarditis, thrombo-embolic events and hemolysis) and 20 other late complications (anticoagulant-related hemorrhage, arrhythmias or congestive heart failure) occurred in 22 patients. The linearized rate for all late complications is 5.8% per patient-year. The influence of eight preoperative variables on overall mortality and late valve-related complications was assessed: age, valve(s) affected, active or healed infection, bacteriology, annular abscess, emergency or elective surgery, preoperative renal function and NYHA class. ...Continue Reading

Citations

Jul 6, 2000·The Annals of Thoracic Surgery·C AlexiouJ L Monro
Apr 11, 2014·Heart, Lung & Circulation·B DunneR Larbalestier
May 11, 2005·International Journal of Cardiology·Walter KnirschPeter E Lange
Nov 18, 2005·American Heart Journal·Christopher H CabellUNKNOWN International Collaboration on Endocarditis Merged Database (ICE-MD) Study Group Investigators
Apr 4, 1998·The Annals of Thoracic Surgery·P RuchatH Sadeghi
Jun 1, 1997·Japanese Circulation Journal·J IemuraH Shirotani
Jun 26, 2007·The Annals of Thoracic Surgery·Andrea ColliTiziano Gherli
Feb 22, 2007·Journal of Cardiovascular Medicine·Roberto MocchegianiMaura Nataloni

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