Surgical ampullectomy: an underestimated operation in the era of endoscopy

HPB : the Official Journal of the International Hepato Pancreato Biliary Association
Lutz SchneiderThilo Hackert

Abstract

Benign neoplastic, inflammatory or functional pathologies of the ampulla of Vater are mainly treated by primary endoscopic interventions. Consequently, transduodenal surgical ampullectomy (TSA) has been abandoned in many centres, although it represents an important tool not only after unsuccessful endoscopic treatment. The aim of the study was to analyse TSA for benign lesions of the ampulla of Vater. All patients who underwent TSA between 2001 and 2014 were included. Patients were analysed in terms of indications, postoperative morbidity and mortality as well as long-term success. Eighty-three patients underwent TSA. Indications included adenomas in 44 and inflammatory stenosis in 39 patients. 96% of the patients had undergone endoscopic therapeutic approaches prior to TSA (median no. of interventions n = 3). Postoperative morbidity occurred in 20 patients (24%). There was one procedure-associated death (mortality 1.2%). The mean follow-up was 54 months. Long-term overall success rate for TSA was 83.6%. After TSA for ampullary adenoma, the recurrence rate was 4.5%. TSA is an underestimated surgical procedure, which can be performed safely with high long-term efficacy. It can be implemented in clinical algorithms for patients w...Continue Reading

References

Jan 1, 1990·American Journal of Surgery·A L WarshawB Flavin-Warshaw
Mar 1, 1993·Gastrointestinal Endoscopy·K F BinmoellerN Soehendra
Apr 24, 2001·Endoscopy·Z ZádorováJ Hajer
Jul 30, 2002·Gastrointestinal Endoscopy·Ian D NortonMaurits J Wiersema
Jan 28, 2004·Gastrointestinal Endoscopy·Marc F CatalanoDouglas A Howell
Aug 5, 2004·Journal of Gastroenterology·Terumi Kamisawa
Apr 14, 2005·World Journal of Surgery·Elijah DixonPaul D Greig
Jul 9, 2005·Surgery·Claudio BassiUNKNOWN International Study Group on Pancreatic Fistula Definition
Sep 28, 2005·Gastrointestinal Endoscopy·Sabine BohnackerNib Soehendra
Mar 1, 2008·Journal of the American College of Surgeons·Stephen R GrobmyerSteven N Hochwald
Mar 18, 2008·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·P O BerberatM W Büchler
Jul 18, 2009·Gastrointestinal Endoscopy·Shayan IraniRichard A Kozarek
Apr 8, 2011·World Journal of Surgery·Lutz SchneiderJens Werner
Apr 16, 2011·Scandinavian Journal of Gastroenterology·Odile Jeanniard-MaletMarc Giovannini
Nov 24, 2011·Journal of the Korean Surgical Society·Jieun KimKee-Taek Jang
Jun 13, 2012·Langenbeck's Archives of Surgery·Thomas C HallGiuseppe Garcea
Mar 4, 2014·World Journal of Gastroenterology : WJG·Giovanni D De Palma
Jun 12, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Edwin O OnkendiFlorencia G Que
Nov 5, 2014·Gut and Liver·Jong Ho MoonYun Nah Lee

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Citations

Aug 29, 2017·Journal of Hepato-biliary-pancreatic Sciences·Takuji KagiyaKenichi Hakamada
Jan 6, 2017·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Verushka M MansukhaniJagannath Palepu
Jun 1, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Alain SauvanetMaxime Palazzo
Aug 17, 2019·World Journal of Clinical Cases·Masaaki HirataKenya Yamanaka
Jul 26, 2018·Langenbeck's Archives of Surgery·A C MilanettoA Zerbi
Apr 26, 2019·United European Gastroenterology Journal·Enrique Pérez-Cuadrado-RoblesPierre H Deprez
Dec 2, 2020·Journal of Hepato-biliary-pancreatic Sciences·Masato NaginoItaru Endo
Jan 3, 2021·Updates in Surgery·Fabio Francesco di MolaPierluigi di Sebastiano
Jan 25, 2021·Asian Journal of Surgery·Yun Kyung JungKyeong Geun Lee
May 1, 2021·Journal of Clinical Medicine·Ugo MarcheseDavid Fuks
May 5, 2021·Surgical Endoscopy·Erik HaraldssonUrban Arnelo
Jul 15, 2021·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·Martin Schneider, Markus W Büchler
Aug 4, 2021·Langenbeck's Archives of Surgery·Taiga WakabayashiYuko Kitagawa
Aug 14, 2021·International Journal of Surgery Case Reports·Susan PradhanRamesh Singh Bhandari
Feb 5, 2021·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Pietro GambittaMaurizio Vertemati

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