Surgical Application of the Suboccipital Subtonsillar Approach to Reach the Inferior Half of Medulla Oblongata Tumors in Adult Patients

Frontiers in Surgery
Alejandra T RabadánDiego Hernández

Abstract

Medulla oblongata (MO) tumors are uncommon in adults. Controversies about their treatment arise regarding the need for histological diagnosis in this eloquent area of the brain, weighing benefits of a reliable diagnosis, and the potential disadvantages of invasive procedures. As a broader variety of pathological findings could be found in this localization, the accurate histopathological definition could not only allow an adequate therapy but also can prevent the disastrous consequences of empiric treatments. There are few publications about their surgical management and all belongs to small retrospective cohorts. In this scenario, we are reporting two patients with exophytic or focal lesions in the inferior half of the medulla, who underwent surgery by suboccipital midline subtonsillar approach. This approach was not specifically described to reach MO before, and we found that the lesions produced a mild elevation of the tonsils providing a wide surgical view from the medulla to the foramen of Luchska laterally, and up to the middle cerebellar peduncle, offering a wide and safe access.

References

Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·D C ShrieveV A Levin
Jan 1, 1991·Acta neurochirurgica. Supplementum·A BricoloA Talacchi
Jan 1, 1991·British Journal of Neurosurgery·S NishioM Fukui
Jan 1, 1995·Advances and Technical Standards in Neurosurgery·A Bricolo, S Turazzi
Jan 15, 1993·International Journal of Radiation Oncology, Biology, Physics·M J GuineyK Narayan
Oct 22, 1998·Neurology·J C LandolfiL M DeAngelis
Sep 13, 2000·Neurosurgery·A L Rhoton
Nov 10, 2001·Brain : a Journal of Neurology·J S GuillamoUNKNOWN Association des Neuro-Oncologues d'Expression Française (ANOCEF)
Mar 27, 2003·Neurosurgery·Walter C JeanHarry R van Loveren
Jul 8, 2003·Neurosurgical Review·Abdulvahap GökIbrahim Erkutlu
Nov 6, 2003·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·E J BoviatsisD E Sakas
Dec 4, 2003·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Kazuhiko KyoshimaJun Nakayama
Aug 27, 2005·British Journal of Neurosurgery·K MurschJ Behnke-Mursch
Jan 30, 2008·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Mark A RosenthalGraham G Giles
Feb 23, 2008·Journal of Neurology·A SalmaggiUNKNOWN Associazione Italiana di Neuro-oncologia
Jun 13, 2009·Journal of Neurology, Neurosurgery, and Psychiatry·W RachingerF W Kreth
Sep 29, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·José L Pérez-GómezFernando Rueda-Franco

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Methods Mentioned

BETA
biopsy
dissection
imaging techniques
biopsies

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