Surgical complications after intestinal transplantation in infants and children--UK experience

Journal of Pediatric Surgery
Girish L GupteAlastair J W Millar

Abstract

Surgical complications have a significant impact on morbidity and mortality following intestinal transplantation (ITx). Birmingham Children's Hospital commenced intestinal transplantation in 1993 and the following surgical strategies evolved: (a) pretransplant abdominal tissue expanders, 1998; (b) combined en-bloc reduced liver and intestinal transplantation (CRLITx), 1998; (c) staged abdominal closure, 2001; (d) preservation of graft duodenal artery, 2005. An internal audit was performed to document the surgical complications after ITx and to evaluate strategies in the management and prevention of complications. A retrospective analysis of the medical records from January 1993 to June 2007 was conducted to identify surgical complications, evaluate management strategies, and report outcome following ITx. Forty-six children underwent 49 ITx (9 isolated intestinal, 39 combined liver and intestinal [CLITx], and 1 multivisceral transplant). Twenty three children had CRLITx since 1998, although there were none before 1997. The median donor: recipient weight ratio in CLITx was 2.2:1 (range, 0.67:1-6.70:1). Twenty-six children experienced 29 (59%) surgical complications: portacaval shunt thrombosis (n = 2, none alive); graft duodenal ...Continue Reading

References

Mar 14, 1998·Journal of Pediatric Surgery·E A BeierleS P Dunn
Mar 14, 1998·Journal of Pediatric Surgery·J ReyesT E Starzl
Jul 29, 2004·Transplantation·Thomas M Fishbein
Mar 31, 2005·Annals of Surgery·David GrantUNKNOWN Intestine Transplant Registry
Jun 15, 2006·Annals of Surgery·Tomoaki KatoPhillip Ruiz
Jul 5, 2006·Seminars in Pediatric Surgery·Jorge D Reyes

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Citations

Apr 7, 2012·Critical Care Research and Practice·J Chiaka Ejike, Mudit Mathur
Feb 21, 2016·Radiologic Clinics of North America·A Luana StanescuGrace S Phillips
May 7, 2014·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·H GieleA Vaidya
Aug 2, 2016·Transplantation Reviews·Laurens J CeulemansJacques Pirenne
Nov 28, 2016·Transplant International : Official Journal of the European Society for Organ Transplantation·Florence LacailleChristophe Chardot
Sep 24, 2015·Plastic and Reconstructive Surgery·Justin M BroylesJustin M Sacks
Mar 25, 2020·Critical Care : the Official Journal of the Critical Care Forum·Inneke E De LaetJan J De Waele
Aug 12, 2015·Current Opinion in Organ Transplantation·Esther Ramos Boluda

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