Surgical complications after transsphenoidal microscopic and endoscopic surgery for pituitary adenoma: a consecutive series of 506 procedures

Acta neurochirurgica
Helene HalvorsenEirik Helseth

Abstract

This single-institution, consecutive series of transsphenoidal procedures included all patients in a defined population of 2.6 million inhabitants who underwent surgery during a specific time period. We sought to determine the surgical complication rate and overall survival rate after transsphenoidal surgery for pituitary adenoma. All transsphenoidal procedures for histologically verified pituitary adenomas performed between September 2002 and February 2011 at our institution were included in this study. The data were obtained from a prospectively collected database and from reviewing medical records. No patients were lost to follow-up, and the median follow-up time was 28 months. A total of 506 transsphenoidal procedures were performed on 446 patients. There were 268 microscopic and 238 endoscopic procedures involving 352 non-functioning and 154 hormone-secreting adenomas. A total of 73% of the procedures were primary surgeries, and 27% were repeat surgeries for tumor recurrence. The overall complication rate was 9.1%. The three most frequent complications were cerebrospinal fluid (CSF) leakage (4.7%), meningitis (2%), and visual deterioration (2%). Multivariate analyses showed that the overall risk for complications increased...Continue Reading

References

Oct 13, 1998·The Journal of Clinical Endocrinology and Metabolism·A AboschC B Wilson
Apr 20, 1999·Endocrinology and Metabolism Clinics of North America·E R Laws, K Thapar
Jul 26, 2000·Baillière's Best Practice & Research. Clinical Endocrinology & Metabolism·R N Clayton
Nov 18, 2000·Pituitary·E R Laws
Jan 5, 2002·Journal of Neuro-oncology·H D Jho
Aug 21, 2002·Journal of Neurosurgery·Paolo CappabiancaEnrico de Divitiis
Dec 18, 2002·Neurosurgery·Enrico de Divitiis, Paolo Cappabianca
Oct 15, 2003·The Journal of Clinical Endocrinology and Metabolism·Fred G BarkerBrooke Swearingen
Jan 25, 2006·Minimally Invasive Neurosurgery : MIN·M S KabilH K Shahinian
Oct 19, 2006·Neuroendocrinology·Giorgio FrankMarco Faustini Fustini
Oct 10, 2007·Brazilian Journal of Otorhinolaryngology·Rodrigo de Paula SantosLuc Louis Maurice Weckx
Jun 26, 2010·The Laryngoscope·Brian RotenbergNeil Duggal
Sep 18, 2010·Clinical Endocrinology·Mohammad Hassan MuradVictor M Montori
Jul 1, 2011·The Journal of Clinical Endocrinology and Metabolism·John A JaneMary Lee Vance
Jul 15, 2011·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·J K GoudakosC Georgalas
Jan 19, 2012·The Laryngoscope·Timothy R DeKlotzZiad Deeb
Mar 27, 2012·Journal of Neurosurgery·Brian J DlouhyJeremy D W Greenlee

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Citations

Aug 8, 2015·International Forum of Allergy & Rhinology·Caitlin C BolingRodney J Schlosser
Apr 14, 2016·Endocrine·Kristin Astrid ØysteseJens Bollerslev
Oct 30, 2016·Journal of Neurosurgery·Hazem M NegmTheodore H Schwartz
Feb 13, 2016·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·V LeviM Locatelli
Mar 17, 2017·World Neurosurgery·Tasneem ShikaryLee A Zimmer
Dec 28, 2017·Pituitary·David L PennEdward R Laws
Oct 27, 2017·Endocrine·Pietro MortiniMarco Losa
Feb 9, 2018·British Journal of Neurosurgery·Hamideh AkbariAmeneh Ebrahim Valojerdi
Feb 6, 2019·Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko·N I MikhaylovI A Savin
Feb 24, 2019·Journal of Neurosurgery·Anthony O Asemota, Gary L Gallia
Jul 23, 2019·International Forum of Allergy & Rhinology·Eric W WangCarl H Snyderman
Oct 22, 2016·The Journal of Craniofacial Surgery·Huang Guo-DongLi Wei-Ping
Jul 28, 2019·Journal of Neurosurgery·Simona Mihaela FloreaHenry Dufour
Aug 1, 2018·Pituitary·Jürgen Honegger, Florian Grimm
Nov 18, 2019·Current Urology Reports·Shiri LevySudhaker D Rao
Feb 18, 2020·BMC Neurology·Magdalena Chrościńska-KrawczykMaria Klatka
Aug 13, 2020·Neurosurgical Review·Leandro Custódio do AmaralAlexandre Varella Giannetti
Feb 25, 2015·The Journal of Craniofacial Surgery·Hansheng ShuLiemei Guo
Feb 28, 2017·Neurologia Medico-chirurgica·Hiroshi Nishioka
Jul 9, 2020·Clinical Medicine Insights. Endocrinology and Diabetes·Mussa H AlMalkiSalem A Beshyah
Feb 22, 2021·Journal of Neuro-oncology·Navid RedjalBrian V Nahed
Jul 22, 2019·Best Practice & Research. Clinical Endocrinology & Metabolism·Philippe Chanson, Dominique Maiter
Jun 15, 2021·Mayo Clinic Proceedings·Jamie J Van GompelWilliam L Lanier
Jul 27, 2021·Journal of Neurological Surgery. Part B, Skull Base·Mark B ChaskesJames J Evans

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