Hypoplastic left heart syndrome is a congenital heart defect characterized by hypoplasia of left heart structures. Over the past 3 decades, there have been advances in techniques and management in the care of these patients. We discuss shunt selection, operative strategies, transplantation, and outline various facets of management at the University of Florida. This is a review of the literature highlighting some of the technical aspects of the preoperative, operative, and postoperative care that are important in today's management of hypoplastic left heart syndrome.
Trends and outcomes after prenatal diagnosis of congenital cardiac malformations by fetal echocardiography in a well defined birth population, Atlanta, Georgia, 1990-1994
The relation between right ventricular function and left ventricular morphology in hypoplastic left heart syndrome: angiographic and pathological studies
Modified Norwood procedure with a high-flow cardiopulmonary bypass strategy results in low mortality without late arch obstruction
Hypoplastic left heart syndrome with intact or highly restrictive atrial septum: outcome after neonatal transcatheter atrial septostomy
Fate of infants with hypoplastic left heart syndrome listed for cardiac transplantation: a multicenter study
Cardiac magnetic resonance imaging after stage I Norwood operation for hypoplastic left heart syndrome
Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion
Single-ventricle palliation for high-risk neonates: the emergence of an alternative hybrid stage I strategy
The relationship of postoperative electrographic seizures to neurodevelopmental outcome at 1 year of age after neonatal and infant cardiac surgery
Growth and correlates of nutritional status among infants with hypoplastic left heart syndrome (HLHS) after stage 1 Norwood procedure
In-hospital mortality for children with hypoplastic left heart syndrome after stage I surgical palliation: teaching versus nonteaching hospitals
Impact of preoperative treatment strategies on the early perioperative outcome in neonates with hypoplastic left heart syndrome
Birth weight and complexity are significant factors for the management of hypoplastic left heart syndrome
Regional low-flow perfusion versus circulatory arrest in neonates: one-year neurodevelopmental outcome
Moderately hypothermic cardiopulmonary bypass and low-flow antegrade selective cerebral perfusion for neonatal aortic arch surgery
Neurodevelopmental and neuroradiologic outcomes in patients with univentricular heart aged 5 to 7 years: related risk factor analysis
Improving the outcome of high-risk neonates with hypoplastic left heart syndrome: hybrid procedure or conventional surgical palliation?
Risk factors for hospital morbidity and mortality after the Norwood procedure: A report from the Pediatric Heart Network Single Ventricle Reconstruction trial
Interstage mortality after the Norwood procedure: Results of the multicenter Single Ventricle Reconstruction trial
Staged left ventricular recruitment after single-ventricle palliation in patients with borderline left heart hypoplasia
Tricuspid valve repair improves early right ventricular and tricuspid valve remodeling in patients with hypoplastic left heart syndrome
Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.