Surgical excision for recurrent herpes simplex virus 2 (HSV-2) anogenital infection in a patient with human immunodeficiency virus (HIV)

Infection
Folasade ArinzeStephen Raffanti

Abstract

Recurrent anogenital herpes simplex virus infections are common in patients with human immunodeficiency virus (HIV), of whom approximately 5% develop resistance to acyclovir. We present a case of a 49-year-old man with HIV who had an 8-year history of recurrent left inguinal herpes simplex virus type 2 ulcerations. He initially responded to oral acyclovir, but developed resistance to acyclovir and eventually foscarnet. The lesion progressed to a large hypertrophic mass that required surgical excision, which led to resolution without recurrences. Our case highlights the importance of surgical excision as a treatment option in refractory herpes simplex virus anogenital infections.

References

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Citations

Jun 6, 2019·Infection·Bijan Koushk-JalaliAlexander Kreuter
Jan 14, 2020·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Bruna Morassi SassoRafael Fantelli Stelini

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