Surgical experience in treating T4 lung cancer: its resectability, morbidity, mortality and prognosis

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
C P HsuC Y Chen

Abstract

Extensive experience in the treatment of locally advanced lung cancers is rare. The aim of this study is to show the rationality and effectiveness of an aggressive surgical approach in T4 lung cancers. Between 1984 and 1994, 111 consecutive cases of T4 lung cancers were operated on. The patients included 91 males and 20 females, with mean ages of 61.8 years and 55.3 years, respectively. The cell types included 57 squamous cell carcinomas, 42 adenocarcinomas, and 12 miscellaneous malignancies. Fifty-three (47.7%) procedures were non-resectional. The remaining 58 (52.3%) procedures had various extents of pulmonary resection. These surgical procedures included 24 (21.6%) pulmonary resections with gross residual tumour (R2), nine (8.1%) pulmonary resections with microscopic residual tumour (R1), and 25 (22.5%) curative pulmonary resections without residual tumour (R0). Post-operative adjuvant therapy included radiotherapy ( > or = 3000 rads) in 53 patients (47.7%), and cisplatin-based chemotherapy in 15 patients (13.5%). The overall median survival time of these 111 patients was 9.1 months. The overall cumulative survival rates at 1, 2, 3 and 5 years were 38.0%, 20.4%, 15.3%, and 5.5%, respectively. There were 24 (21.6%) complicati...Continue Reading

References

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Citations

Mar 6, 2015·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Hidenori KusumotoYoshiki Sawa
Aug 28, 2007·The Annals of Thoracic Surgery·Jagan RaoGail E Darling
Jul 4, 2001·The Journal of Thoracic and Cardiovascular Surgery·T OkumuraR Tsuchiya
Jul 28, 2009·The Annals of Thoracic Surgery·Hao-xian YangJian-hua Fu
Jun 22, 2005·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jung Hwa HwangDong Erk Goo
Apr 26, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Deniz ArslanBurhan Savas

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