Surgical Fixation of Metacarpal Shaft Fractures Using Absorbable Implants: A Systematic Review of the Literature

Hand : Official Journal of the American Association for Hand Surgery
Jessica HazanStephanie Thibaudeau

Abstract

Despite the proven efficacy and advantages of absorbable implants, their use for metacarpal shaft fixation has been limited. This is likely due to the high reported complication rates in early studies with polyglycolic acid (PGA) implants, notably high rates of noninfectious inflammatory reaction (5%-25%), occurring up to 30 weeks after fixation. The objective of this study was to assess the clinical outcomes of newer absorbable plates and screws in the treatment of metacarpal shaft fractures. The authors performed a systematic search of the PubMed, Ovid MEDLINE, and EMBASE databases dating from 1946 to 2017. Primary outcome measures were the development of noninfectious inflammatory reaction and implant failure. A total of 42 metacarpal shaft fractures in 35 patients were included. The average follow-up time was 20.4 months (n = 24; range: 3.6-61 months). Only 1 case (2.4%) of noninfectious inflammatory reaction was reported with polylactic acid (PLA) plates and PLA/PGA compounds. Noninfectious inflammatory reaction was observed in 4 out of the 9 patients (44.4%) with a trimethylene carbonate/PLA compound. Symptoms appeared after an average time of 15.8 months (range: 12-19 months) post-fixation. Painless prolonged inflammatio...Continue Reading

References

Jul 24, 2001·The Journal of Hand Surgery·K J BozicJ B Jupiter
Mar 20, 2002·The Journal of Trauma·Cesare FusettiMichael Papaloïzos
Aug 21, 2002·Annals of Plastic Surgery·Gerald T Lionelli, Richard A Korentager
May 29, 2003·Clinical Orthopaedics and Related Research·Eero WarisYrjö T Konttinen
May 14, 2004·The Journal of Hand Surgery·Eero WarisNureddin Ashammakhi
Nov 16, 2004·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·E WarisJ Vasenius
Oct 19, 2006·Injury·Michael L Bernstein, Kevin C Chung
Apr 3, 2007·The Journal of Hand Surgery·Clemens DumontKlaus Michael Stürmer
Feb 23, 2010·International Journal of Surgery·David MoherUNKNOWN PRISMA Group
May 18, 2010·Clinical Orthopaedics and Related Research·Panagiotis K GivissisAnastasios G Christodoulou
Apr 27, 2010·Current Biology : CB·Jeremy M Wolfe
Sep 21, 2012·The Journal of Bone and Joint Surgery. American Volume·Akinori SakaiToshitaka Nakamura
Jul 29, 2015·Archives of Plastic Surgery·Jung-Sik ChoiYoung-Joon Jun

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Citations

Oct 9, 2019·Plastic and Reconstructive Surgery. Global Open·Yehuda ChocronSabrina Cugno
Oct 30, 2019·Hand : Official Journal of the American Association for Hand Surgery·Andrew SephienFrancisco A Schwartz-Fernandes
Mar 19, 2021·Regenerative Biomaterials·Jiazhen ZhangBin Ma

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