Surgical infections in the traumatized spine

Clinical Orthopaedics and Related Research
Moe R LimAlexander R Vaccaro

Abstract

Patients with acute spinal injury who require operative intervention may be at increased risk for postoperative surgical-site infection when compared with patients having elective spinal surgery. Various local, systemic, and iatrogenic factors predispose this unique population of patients to post-surgical infection. Nonmodifiable risk factors for surgical-site infection in spine trauma include age, medical comorbidities, and neurologic status. Modifiable risk factors include poor postoperative nutritional status, delay from time of injury to surgical intervention, posterior surgical approach, higher number of levels stabilized, length of postoperative stay in the intensive care unit, and treatment by a single specialty team (versus treatment by successive orthopaedic and neurosurgical teams). When treating patients with spine trauma, a high index of suspicion should be maintained for patients with multiple risk factors for infection and every effort should be made to minimize the modifiable risk factors. Level V (expert opinion). Please see the Guidelines for Authors for a complete description of levels of evidence.

References

Jan 1, 1991·Archives of Surgery·S E PoriesP Vacek
Feb 1, 1988·The Journal of Hospital Infection·A Hambraeus
Mar 1, 1987·Journal of Neurosurgery·L F MarshallG L Clifton
Jan 6, 1984·JAMA : the Journal of the American Medical Association·M B BrackenP L Perot
Jun 1, 1997·Journal of Neurosurgery·A D LeviV K Sonntag
Sep 25, 1997·Spinal Cord·D J RodriguezF W Clevenger
Mar 13, 1999·Critical Care Medicine·G P Zaloga
Oct 29, 2000·Journal of Spinal Disorders·M A WeinsteinF P Cammisa
Nov 21, 2000·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·S SauerlandE A Neugebauer
Dec 26, 2001·Journal of Orthopaedic Trauma·G R RechtineA M Chrin
Feb 6, 2003·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Thomas KälickeStephan Arens
Mar 26, 2003·Journal of Neurosurgery·Margaret A OlsenVictoria J Fraser
Apr 15, 2004·Spine·Erwin M BrownUNKNOWN British Society for Antimicrobial Chemotherapy Working Party on Neurosurgical Infections
Sep 7, 2004·Neurosurgical Focus·John M BeinerAlexander R Vaccaro

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Citations

May 4, 2010·Journal of Neurosurgery. Spine·Masahiko WatanabeJoji Mochida
Nov 26, 2009·Journal of Neurosurgery. Spine·John E O'TooleRichard G Fessler
Jan 19, 2013·World Journal of Orthopedics·Vishal HegdeRussel C Huang
Oct 2, 2015·Neurosurgical Focus·Ethan A WinklerPhiroz E Tarapore
Oct 30, 2014·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Shih-Hao ChenShan-Yin Tsai
Mar 4, 2008·The Journal of Bone and Joint Surgery. British Volume·F CanaveseK M Emara
Jun 13, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Rui M Duarte, Alexander R Vaccaro
Apr 22, 2015·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Erol OksuzUnal Erkorkmaz
May 15, 2021·Operative Neurosurgery·William W WroeJoseph C Hsieh

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