Surgical management and outcome of synovial sarcoma in the spine

World Journal of Surgical Oncology
Minglei YangJianru Xiao

Abstract

Synovial sarcoma (SS) is a soft tissue sarcoma that rarely occurs in the spine, and a minimal number of cases have been reported in the literature. Spinal SS is challenging in diagnosis and treatment and has a poor prognosis. The aim of this study was to summarize and analyse the clinical features and outcomes of patients with spinal SS. A total of 16 cases of patients with spinal SS admitted to our institution were reviewed retrospectively. General information, radiological findings and treatment strategies were collected. These patients were followed up regarding their continuing treatment, local or distant recurrence and survival. Spinal SS patients in this series ranged in age from 12 to 68 years (median, 33). Four en bloc resections and 12 piecemeal resections were performed. Improved Frankel (P = 0.002), visual analogue scale (P = 0.002) and Karnofsky Performance Status (P = 0.002) scores were seen postoperatively. The mean follow-up period was 35.9 ± 23.5 (median 31.5, range 4-87) months, with four local recurrences and three distant metastases detected. Eight patients (50.0%) died of disease by the last follow-up. The 1-, 3- and 5-year overall survival rates were 87.5%, 61.4% and 40.9%, respectively. Preoperative chemot...Continue Reading

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Citations

Oct 8, 2020·Surgical Neurology International·Fayez Dhafer AlshehriAhmed Ibrahim Lary
Oct 16, 2020·Neuro-Chirurgie·D Zimelewicz ObermanJ L Amorim Correa

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Methods Mentioned

BETA
surgical resection
biopsy

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