Surgical management and outcomes of colorectal cancer liver metastases.

The British Journal of Surgery
E J A MorrisG Poston

Abstract

This population-based study investigated the frequency of hepatic resections for colorectal cancer metastases across England and their outcome. Individuals who underwent surgery for colorectal cancer between January 1998 and June 2004 within the English National Health Service were identified via the National Cancer Data Repository. All episodes of care in the 3 years after the initial operation were examined to determine the frequency of liver resection. Variations in the use of liver resection and survival were assessed. Some 114 155 individuals underwent surgery for colorectal cancer over the study period, of whom 3116 (2.7 per cent) subsequently had one or more hepatic resections. The hepatectomy rate increased from 1.7 per cent in 1998 to 3.8 per cent in 2004. There was significant variation in the rate of liver resection across cancer networks (range 1.1-4.3 per cent) and hospitals (range 0.7-6.8 per cent). The crude 5-year survival rate after liver resection was 44.2 (95 per cent confidence interval (c.i.) 42.4 to 46.1) per cent from the time of hepatectomy and 45.9 (95 per cent c.i. 44.1 to 47.7) per cent from the time of colectomy. This was comparable to the 5-year survival rate of patients with stage III disease (42.2...Continue Reading

Associated Clinical Trials

References

Nov 1, 1983·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J R AndersonR D Gelber
Nov 1, 1983·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C J LahrC M Balch
Jan 10, 2001·Cancer·M P ColemanB De Stavola
Apr 1, 2004·British Journal of Cancer·M P ColemanJ Estève
Apr 6, 2004·Ultrasound in Medicine & Biology·Kwok-Sui LeungWing-Hoi Cheung
Sep 30, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Graeme J PostonJames P Kahan
Jul 22, 2006·Annals of Surgery·Sylvain ManfrediAnne-Marie Bouvier
Aug 15, 2006·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Eric Van CutsemUNKNOWN European Colorectal Metastases Treatment Group
Sep 4, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Bernard NordlingerUNKNOWN European Colorectal Metastases Treatment Group
Aug 20, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Graeme J PostonMichael I D'Angelica
Nov 27, 2008·British Journal of Cancer·U NurUNKNOWN AXIS collaborators
May 28, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Scott KopetzRobert R McWilliams

❮ Previous
Next ❯

Citations

Jul 13, 2011·International Journal of Colorectal Disease·Christina HacklHans J Schlitt
Aug 27, 2013·International Journal of Colorectal Disease·Silke SchüleAnnelore Altendorf-Hofmann
Apr 10, 2012·Clinical & Experimental Metastasis·Andreas PichornerUlrike Stein
Sep 14, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Mathias WorniBryan M Clary
May 25, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H SorbyeB Glimelius
Aug 5, 2011·British Medical Bulletin·Robert P Sutcliffe, Satyajit Bhattacharya
Mar 14, 2013·World Journal of Gastroenterology : WJG·Giacomo PuppaAxel Stang
Aug 23, 2012·World Journal of Gastrointestinal Oncology·Rouzbeh MostaediVijay P Khatri
May 8, 2014·World Journal of Gastroenterology : WJG·Jun LiKe-Feng Ding
Mar 4, 2014·Journal of Visceral Surgery·A StoltzM Rivoire
Mar 4, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G FolprechtC-H Köhne
Jun 24, 2014·International Journal of Colorectal Disease·Shahid AhmedNayyer Iqbal
Nov 6, 2013·Surgery Today·Liat SorskiShamgar Ben-Eliyahu
May 3, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Jeroen MertensC Van de Wiele
Jun 25, 2014·Nature Reviews. Clinical Oncology·David A PalmaRalph Weichselbaum
Jun 9, 2015·PET Clinics·Morsal SamimMarnix G E H Lam
Sep 6, 2014·World Journal of Surgery·L I Olsson, F Granstrom
Jul 24, 2014·Clinical & Experimental Metastasis·Moritz J StrowitzkiMichael D Menger
Oct 29, 2011·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·G Folprecht, W O Bechstein
Feb 1, 2013·Clinical Journal of Gastroenterology·Tadashi TsukamotoShoji Kubo
Jan 20, 2015·Journal of Surgical Oncology·Thomas SchmidtAlexis Ulrich
Aug 21, 2012·Journal of the Chinese Medical Association : JCMA·Chao-Wen HsuJui-Ho Wang
Dec 26, 2015·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A NorénL I Olsson
Dec 4, 2015·Annals of Surgical Oncology·Robert P Jones, Graeme J Poston
Mar 20, 2013·Current Problems in Surgery·Lawrence M KnabDavid M Mahvi
Jan 23, 2016·Clinical Oncology : a Journal of the Royal College of Radiologists·F Macbeth, T Treasure
Dec 4, 2012·Critical Reviews in Oncology/hematology·D GrünhagenG J Poston
Jun 12, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G A M van WalsumUNKNOWN Dutch Liver Surgeons Group
May 10, 2012·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Lakhbir SandhuCarol-Anne Moulton
Aug 9, 2011·Clinical Colorectal Cancer·Steven R Alberts, Graeme J Poston
Sep 12, 2015·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Victor M ZaydfudimTraci L Hedrick
Feb 1, 2013·The British Journal of Surgery·M N MavrosT M Pawlik

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved