Surgical Management of Haemophilic Pseudotumors: Experience in a Developing Country

Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research
Yu HeYong Liu

Abstract

Hemophilic pseudotumors result from repeated episodes of bleeding into bone, subperiosteum, and soft tissue. Since clotting factors became available, uncontrolled perioperative bleeding is a less significant problem for surgeons in developed countries. However, they are more difficult to come by in China. Additionally, patients often have to undergo surgery for giant masses and suffer complications. We wanted to present our experience in the surgical management of hemophilic pseudotumors over a 40-year period. We retrospectively reviewed 429 hemorrhagic coagulopathy patients between 1983 and 2015. Diagnosis of hemophilic pseudotumor was confirmed following clinical, radiological, and pathological criteria. The data were recorded and analyzed: type and severity of hemophilia, presence of inhibitor, etiological antecedent, localization of pseudotumors, clinical signs, surgical management and outcomes. Eighteen pseudotumor patients underwent surgical treatment. All of them were male, with mean age of 34.3 years. Fifteen patients had hemophilia A and three patients had hemophilia B. There were twelve proximal and two distal pseudotumor patients. The mean follow-up was 51.9 months. For pseudotumors in the extremities, complete surgi...Continue Reading

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Citations

Aug 10, 2019·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Daniel P HartMike Makris
Jul 16, 2020·Haemophilia : the Official Journal of the World Federation of Hemophilia·Xueqing DouRenchi Yang
Jul 24, 2020·Haemophilia : the Official Journal of the World Federation of Hemophilia·Shiyuan LinZihang Feng
Nov 4, 2020·Haemophilia : the Official Journal of the World Federation of Hemophilia·Jianxiong ZhengBin Chen
Mar 30, 2021·Open Medicine·Kunzhe LinFan Zhang

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