Surgical management of intraductal papillary mucinous neoplasm with main duct involvement: an international expert survey and case-vignette study

Surgery
Lianne ScholtenEuropean Study Group on Cystic Tumours of the Pancreas and the International Association of Pancreatology

Abstract

The risk of invasive cancer in resected intraductal papillary mucinous neoplasm with main pancreatic duct involvement is 33%-60%. Most guidelines, therefore, advise resection of main duct intraductal papillary mucinous neoplasm and mixed type intraductal papillary mucinous neoplasm in surgically fit patients, although advice on the surgical strategy (partial or total pancreatectomy) differs. We performed a survey amongst international experts to guide the design of future studies and help to prepare for a single international set of guidelines. An online survey including case vignettes was sent to 221 international experts who had published on main duct/mixed type intraductal papillary mucinous neoplasm in the previous decade and to all surgeon and gastroenterologist members of the pancreatic cyst guideline committees of the European Study Group and the International Association of Pancreatology. Overall, 97 experts (67 surgeons, 30 gastroenterologists) from 19 countries replied (44% response rate). Most (93%) worked in an academic hospital, with a median of 15 years' experience with intraductal papillary mucinous neoplasm treatment. In main duct/mixed type intraductal papillary mucinous neoplasm patients with pancreatic duct d...Continue Reading

Citations

Sep 19, 2019·Nature Reviews. Gastroenterology & Hepatology·Nadine C M van HuijgevoortMarc G Besselink
Sep 29, 2019·Annals of Surgical Oncology·Thomas F StoopMarco Del Chiaro
Sep 11, 2019·The British Journal of Surgery·L ScholtenUNKNOWN Dutch Pancreatic Cancer Group
Jul 10, 2020·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·B W RenzJ Werner
Dec 11, 2020·Gastroenterology·Katherine S YangRalph Weissleder
Apr 4, 2021·Journal of Clinical Medicine·Margaret G Keane, Elham Afghani
Apr 24, 2021·Surgical Oncology·Matteo PalmeriLuca Morelli

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