Surgical margins in the management of extremity soft tissue sarcoma

Chinese Clinical Oncology
Makoto Endo, Patrick P Lin

Abstract

Standard treatment of localized soft tissue sarcoma should include surgical resection, which can be performed alone or in combination with perioperative radiotherapy and/or chemotherapy. The purpose of surgical intervention is to excise the tumor completely and to prevent disease relapse. Surgeons should remove the tumor with a sufficiently wide margin of the surrounding normal tissue; however, it is also necessary to pay attention to maximizing postoperative physical function. In order to balance the two competing goals, surgeons have been working to establish better methods for determining surgical margins and better guidelines for achieving adequate margins. At the present time, limb-sparing surgery is the mainstay of surgical treatment for soft tissue sarcomas of the extremities. In this article, we review the fundamentals of surgical margins as they pertain to soft tissue sarcomas and make recommendations for surgical treatment based upon current literature.

Citations

Nov 22, 2019·Veterinary and Comparative Oncology·Antonella BorgattiJessica Lawrence
Aug 22, 2020·Expert Review of Anticancer Therapy·Robert NakayamaMakoto Endo
Aug 21, 2020·Journal of Surgical Oncology·Akihiko TakeuchiHiroyuki Tsuchiya
Jan 25, 2020·Der Orthopäde·Hans Roland DürrAlexander Klein
May 28, 2019·Current Treatment Options in Oncology·Makoto EndoYoshihiro Matsumoto
May 30, 2020·Journal of Orthopaedics·V KurisunkalL Jeys
Feb 18, 2021·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·F MitriF Toberer
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Jun 1, 2021·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Luis Rodrigo Merino-RuedaEduardo J Ortiz-Cruz
May 18, 2021·Seminars in Cell & Developmental Biology·Eszter MihalyWarren Grayson
Aug 2, 2021·The Journal of Hand Surgery·Cheryl Pei Chyi YongSoumen Das De
Aug 11, 2021·Annals of Biomedical Engineering·Vismaya S BachuBetty Tyler

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