Surgical morbidity and clinical outcomes in ovarian cancer - the role of obesity

BJOG : an International Journal of Obstetrics and Gynaecology
Anke SmitsKhadra Galaal

Abstract

To evaluate the effect of body mass index on the surgical outcomes in ovarian cancer patients. In addition, we performed a systematic review to compare our outcomes with the current literature. Retrospective cohort study and a systematic review of the literature. Gynaecology department at the Royal Cornwall Hospital Trust. Surgically managed stage I-IV ovarian cancer patients between September 2006 and September 2014. Primary and secondary outcome measures were evaluated across BMI categories; BMI <25 kg/m², BMI 25-29.9 kg/m², BMI ≥30 kg/m² and BMI ≥40 kg/m². A systematic review was performed according to Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. The primary outcome measure was surgical complications. Secondary outcome measures were other intra- and postoperative outcomes. Two hundred twenty-eight women were included in the study, of which 84 had a BMI <25 kg/m², 84 women had a BMI 25-29.9 kg/m², and 60 women were obese (BMI ≥30 kg/m²), 13 of whom were morbidly obese. Morbid obesity was associated with increased rates of wound complications. However, BMI did not show an association with other outcomes. In the review, an increasing BMI was associated with increased rates of wound com...Continue Reading

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Citations

Jan 16, 2016·Current Oncology Reports·Sarah A PurcellCarla M Prado
Dec 22, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Nathália Silva de PaulaGabriela Villaça Chaves
Feb 15, 2020·The Journal of Bone and Joint Surgery. American Volume·Gregory GlauserNeil R Malhotra
Jul 18, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Young Shin ChungYoung Tae Kim
May 30, 2020·Obstetrical & Gynecological Survey·S Allison StaleyLeslie H Clark
Jan 12, 2021·British Journal of Neurosurgery·Vincent HuangNeil R Malhotra
May 4, 2020·World Neurosurgery·Debanjan HaldarNeil R Malhotra
Feb 6, 2021·Journal of Cachexia, Sarcopenia and Muscle·Jalid SehouliMelisa Guelhan Inci
Dec 10, 2020·Geburtshilfe und Frauenheilkunde·Heinz Kölbl, Thomas Bartl
Feb 15, 2020·World Neurosurgery·Debanjan HaldarNeil R Malhotra
Mar 1, 2021·Clinical Neurology and Neurosurgery·Debanjan HaldarNeil R Malhotra
Jul 15, 2020·World Neurosurgery·Gregory GlauserNeil R Malhotra
Apr 2, 2021·British Journal of Neurosurgery·Ali FarooqiNeil R Malhotra
Apr 13, 2021·Clinical Neurology and Neurosurgery·Ali S FarooqiNeil R Malhotra
Mar 7, 2020·Journal for Healthcare Quality : Official Publication of the National Association for Healthcare Quality·Gregory GlauserNeil R Malhotra
Jun 18, 2021·Journal of Minimally Invasive Gynecology·Maria J SmithBhavana Pothuri
Jun 17, 2020·Journal for Healthcare Quality : Official Publication of the National Association for Healthcare Quality·Debanjan HaldarNeil R Malhotra

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