Surgical outcome of community-acquired Clostridium difficile colitis presenting as toxic megacolon: case report

Surgical Infections
Andrea P MannFariborz Lalezarzadeh


Over the past decade, there has been an increase in both community-acquired and health-care-associated Clostridium difficile colitis secondary to broad-spectrum antibiotic exposure. Toxic megacolon is a rare complication of pseudomembranous colitis that often necessitates emergency colectomy. Review of the pertinent English-language literature. We present a case of community-acquired C. difficile colitis that made its initial presentation as fulminant toxic megacolon. Six months after a total colectomy, the patient has no complaints. Prompt total colectomy may improve survival in patients with toxic megacolon. The incidence of C. difficile-related toxic megacolon and post-operative outcomes of total colectomy should be investigated in a larger observational study.


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Methods Mentioned


Related Concepts

Clostridium Enterocolitis
Megacolon, Toxic
Clostridium difficile (bacteria)
Community-Acquired Infections
Health Care

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