Surgical outcomes and predictors of complication in elderly patients with meningiomas

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Ayman E GalhomM M Ellabban

Abstract

Surgical management of symptomatic meningioma in elderly is still a high-risk surgery due to increased incidence of complication rate. Many scoring systems have been proposed to expect the surgical risk and the outcome.The study tries to assess cranial meningioma surgery in elderly using the Ibañez grade for complication rate and the Geriatric Scoring System (GSS) for the surgical outcome (GSS). A clinical and radiological data were studied retrospectively in 42 patients with a primary intracranial meningioma at or above the age of 65. Complication rate, surgical risk, and outcome were statistically analyzed. The mean Geriatric Scoring System (GSS) score on admission was 15.4 ± 2.6. Ibañez grade of severe complication or death (grades III-IV) were experienced in 26.2% of patients. It was more common in male and in emergency cases, but it was significant in relation to the comorbidities (P < 0.004). Most patients had World Health Organization (WHO) grades I lesions, accounted for 85.7% of patients. MRI evidence of post-surgical residual was 14.4%, and 83.3% of patients had recurrence-free survival (RFS). The GSS score >16 were more frequent in the patient with RFS than those of < 16, and it was statistically significant (P < 0.0...Continue Reading

References

Nov 18, 1998·Annals of Neurology·E WyllieP Ruggieri
Feb 1, 1957·Journal of Neurology, Neurosurgery, and Psychiatry·D SIMPSON
Apr 7, 2005·Acta neurochirurgica·M NakamuraM Samii
Sep 20, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·W KreilG Papaefthymiou
Nov 15, 2005·Neurosurgery·Brian T BatemanMitchell F Berman
Jan 30, 2007·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·F RoserM Nakamura
Nov 6, 2007·The New England Journal of Medicine·Meike W VernooijAad van der Lugt
Dec 20, 2007·Neurosurgery·Oumar SackoHugues Loiseau
Sep 8, 2010·Journal of Neuro-oncology·Joseph WiemelsElizabeth B Claus
May 13, 2011·Acta neurochirurgica·Or Cohen-InbarMenashe Zaaroor
Jun 28, 2011·World Neurosurgery·Federico Alfonso Landriel IbañezAntonio Carrizo
Aug 26, 2011·Neurosurgery·David B SchulChristianto B Lumenta
Mar 13, 2012·Neuro-oncology·Hanna van AlkemadeLukas J A Stalpers
Feb 5, 2013·Pain Practice : the Official Journal of World Institute of Pain·Arif Hussain, Michael Erdek
Jun 6, 2013·Journal of Neuro-oncology·Michael Tin-Chung PoonGilberto Ka-Kit Leung
Dec 29, 2015·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Arash NayeriLola B Chambless
Feb 27, 2016·World Neurosurgery·Shyamal C BirAnil Nanda
Sep 7, 2016·The Lancet Oncology·Roland GoldbrunnerMichael Weller

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Citations

Nov 24, 2018·Journal of Neurosurgical Sciences·Doortje C EngelFlorian H Ebner

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Methods Mentioned

BETA
imaging techniques
biopsy

Software Mentioned

SKALE
SPSS

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