Surgical outcomes in cases of contact lens-related Fusarium keratitis

Eye & Contact Lens
Sonia BelliappaDavid S Chu

Abstract

To examine seven cases of contact lens-related Fusarium keratitis that resulted in therapeutic penetrating keratoplasty, to investigate which factors were associated with favorable versus poor graft outcome in this population. Seven patients who underwent corneal transplant after contact lens-related, culture-proven Fusarium keratitis were identified through a retrospective chart review. The cases occurred between September 2005 and January 2006 at the University of Medicine and Dentistry of New Jersey and Wills Eye Hospital. All seven patients had used Bausch and Lomb's ReNu with MoistureLoc. The outcomes studied were graft status, infection recurrence, and 6-month postoperative visual acuity. The rejection rate was 57.1% and the recurrence rate was 28.6% in this study. No eyes were lost to fungal endophthalmitis. In this population, larger ulcer size and a greater total number of medical agents used before and after penetrating keratoplasty were significantly associated with poor outcomes, namely graft rejection and poor visual acuity. In addition, it was noted that the patients who suffered recurrence of infection had both a larger median graft size and a longer median duration of postoperative antifungal use although these ...Continue Reading

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Citations

Oct 4, 2011·Clinical Ophthalmology·Mohammad Reza SedghipourHassan Dehghan
Aug 3, 2010·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Nathan Efron
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Apr 4, 2021·Journal of Clinical Medicine·Karl Anders KnutssonPaolo Rama

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