Surgical outcomes in patients with endoscopic versus transcranial approach for skull base malignancies: a 10-year institutional experience

British Journal of Neurosurgery
John W RutlandRaj K Shrivastava

Abstract

Object: The authors performed an extensive comparison between patients treated with open versus an endoscopic approach for skull base malignancy with emphasis on surgical outcomes.Methods: A single-institution retrospective review of 60 patients who underwent surgery for skull base malignancy between 2009 and 2018 was performed. Disease features, surgical resection, post-operative morbidities, adjuvant treatment, recurrence, and survival rates were compared between 30 patients who received purely open surgery and 30 patients who underwent purely endoscopic resection for a skull base malignancy.Results: Of the 60 patients with skull base malignancy, 30 underwent open resection and 30 underwent endoscopic resection. The most common hisotype for endoscopic resection was squamous cell carcinoma (26.7%), olfactory neuroblastoma (16.7%), and sarcoma (10.0%), and 43.3%, 13.3%, and 10.0% for the open resection cohort, respectively. There were no statistical differences in gross total resection, surgical-associated cranial neuropathy, or ability to achieve negative margins between the groups (p > 0.1, all comparisons). Patients who underwent endoscopic resection had shorter surgeries (320.3 ± 158.5 minutes vs. 495.3 ± 187.6 minutes (p =...Continue Reading

References

Apr 30, 1993·International Journal of Radiation Oncology, Biology, Physics·L J PetersR A Frankenthaler
Aug 1, 1997·International Journal of Radiation Oncology, Biology, Physics·J T ParsonsR R Million
Jan 5, 2005·The Laryngoscope·John D CaslerEric A Mair
Jul 1, 2008·American Journal of Rhinology·Piero NicolaiPaolo Castelnuovo
Dec 23, 2009·Archives of Otolaryngology--head & Neck Surgery·Ehab HannaMichael Kupferman
Feb 11, 2012·European Annals of Otorhinolaryngology, Head and Neck Diseases·B VerillaudP Herman
Jul 11, 2012·International Forum of Allergy & Rhinology·John W WoodRoy R Casiano
Aug 1, 2014·The Journal of Laryngology and Otology·B SaediA Safavi
Sep 9, 2015·Neurologia Medico-chirurgica·Masahiro ShinNobuhito Saito
May 12, 2016·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Rounak B RawalAdam M Zanation
Mar 10, 2018·JAMA Otolaryngology-- Head & Neck Surgery·Jeremy P HarrisWendy Hara

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