Surgical outcomes of endoscopic management of adenocarcinoma of the sinonasal cavity

Rhinology
Camille JardelezaPeter-John Wormald

Abstract

To report the surgical outcomes of endoscopic resection of adenocarcinomas of the Sinonasal cavity. Retrospective chart review of patients presenting with adenocarcinoma of the anterior skull base between 1998-2008. All patients who underwent wholly endoscopic resection were included in the study. Twelve patients presented with adenocarcinoma involving the sino-nasal cavity. At diagnosis 6 patients were staged as a T2, 5 as a T3 and one as a T4. All of the patients had successful removal of the tumour entirely endoscopically. Three patients recurred: 2 locally and 1 with distant metastases. Overall, 11 patients are alive and free of disease and 1 patient dead of disease. We found an overall disease free survival rate and overall survival rate of 91.6%. The follow-up period ranged from 10 to 96 months with a median of 30 months. Endoscopic management of adenocarcinoma of the sino-nasal cavity can be a viable treatment option to craniofacial resection. With the advancement in endoscopic equipment and surgeon skill, larger tumours may be managed wholly endoscopically.

Citations

Sep 18, 2012·Otolaryngologic Clinics of North America·Rounak B RawalAdam M Zanation
Jun 15, 2012·Acta otorrinolaringológica española·José Luis LlorenteCarlos Suárez
Oct 8, 2011·Otolaryngologic Clinics of North America·Richard J HarveyValerie Lund
Nov 30, 2010·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Luca MuscatelloRiccardo Lenzi
Apr 28, 2011·Head & Neck·Valerie J LundAlfio Ferlito
Mar 26, 2013·European Annals of Otorhinolaryngology, Head and Neck Diseases·F JégouxC Bedfert
Jul 2, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Geoffrey MortuaireAnne-Sophie Thisse

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