Surgical pathology of 104 tricuspid valves (2000-2005) with classic right-sided Ebstein's malformation

Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology
David W BarbaraJoseph A Dearani

Abstract

Ebstein's anomaly has been described extensively in autopsy material. However, there have been no large surgical pathology series of this malformation. To review clinical and surgical pathologic features of a large number of cases of Ebstein's anomaly from a single institution. Review of medical histories, surgical reports, and surgical pathology reports at the Mayo Clinic (2000-2005). Among 104 patients, the mean age was 31 years (2 months-79 years), and 57% were female. Common ECG abnormalities included right bundle branch block (58%), first-degree heart block (31%), preexcitation (18%), and nonspecific intraventricular conduction delay/block (15%). Moreover, 74% had inter-atrial communication, 13% mitral valve prolapse, and 5% bicuspid aortic valve. Clinically, all had tricuspid regurgitation (severe in 74%), and 17% of anterior leaflets were fenestrated. No tricuspid valve was calcified. Surgically, tricuspid tissue was removed during replacement in 99% and repair in 1%. The anterior tricuspid leaflet was resected in 98%, and its length was 0.81-9.3 cm/m2 body surface area (mean, 3.3). Characteristically, leaflets were large and had irregular shapes and numerous short cordal or direct myocardial insertions. One tricuspid va...Continue Reading

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Citations

Sep 25, 2012·Current Treatment Options in Cardiovascular Medicine·Eric V Krieger, Anne Marie Valente
Mar 13, 2014·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Wei WeiShulin Wu
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Jun 23, 2021·Journal of the American Heart Association·Jordan E MorningstarRussell A Norris

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