Surgical removal of submacular hemorrhage using tissue plasminogen activator and perfluorocarbon liquid

American Journal of Ophthalmology
M KameiT Yuasa

Abstract

To assess the result of surgical removal of submacular hemorrhage by using tissue plasminogen activator and perfluorocarbon liquid. In 22 consecutive patients (22 eyes), subretinal hemorrhage associated with age-related macular degeneration, which involved the fovea and completely obscured the choroidal vascular pattern, was treated by pars plana vitrectomy. The hemorrhages were liquefied with tissue plasminogen activator, squeezed into the vitreous cavity with perfluorocarbon liquid, and then evacuated. Efficacy of the procedure was judged by the best postoperative corrected visual acuity, which was 20/100 or better in 16 eyes (73%). Submacular hemorrhage recurred in four (18%) eyes, epiretinal membrane formed in three (14%) eyes, and retinal detachment occurred in three (14%) eyes. Best-corrected final visual acuity was improved postoperatively in 18 (82%) of the 22 eyes, unchanged in three (14%) eyes, and decreased in one (5%) eye, final visual acuity was 20/200 or better in 15 eyes (68%) and limited in other eyes by subretinal hemorrhage of greater than 30 days' duration or subfoveal neovascularizations. Use of tissue plasminogen activator and perfluorocarbon liquid in surgical removal of submacular hemorrhage may improve t...Continue Reading

References

Mar 25, 1992·American Journal of Ophthalmology·H M LambertP F Lopez
May 1, 1991·Archives of Ophthalmology·C A TothM B Landers
Jan 15, 1990·American Journal of Ophthalmology·S R BennettM Klugman
Jul 1, 1990·Archives of Ophthalmology·E C WadeD H Nicholson
Jan 15, 1988·American Journal of Ophthalmology·E de Juan, R Machemer
Dec 1, 1987·Archives of Ophthalmology·T A Hanscom, K R Diddie

❮ Previous
Next ❯

Citations

Dec 4, 2012·Indian Journal of Ophthalmology·Ekta RishiTarun Sharma
Oct 1, 1996·American Journal of Ophthalmology·M H BerrocalH W Flynn
Oct 12, 2012·Japanese Journal of Ophthalmology·Naoko Ueda-ArakawaNagahisa Yoshimura
May 3, 2002·Ophthalmology·Hilel Lewis
Jun 30, 2000·Clinical Eye and Vision Care·T J Stokkermans
Jul 21, 2012·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·P Szurman
May 5, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Christiane I FalknerSusanne Binder
Oct 26, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Takuhiro YamamotoYasuo Tano
May 8, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Wen-Chuan WuYo-Chen Chang
Mar 30, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Takeshi MizutaniYuichiro Ogura
May 30, 1998·Seminars in Ophthalmology·Y IkunoM Kamei
Sep 29, 2011·Journal français d'ophtalmologie·C Chiquet, G Thuret
Jul 28, 2015·Survey of Ophthalmology·Dinu Stanescu-SegallTimothy L Jackson
Mar 21, 2016·Journal français d'ophtalmologie·R BouraouiL El Matri
Aug 24, 1999·American Journal of Ophthalmology·F ShiragaH E Grossniklaus
Nov 3, 2011·Seminars in Ophthalmology·Ryan W Shultz, Sophie J Bakri
Nov 25, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Makoto InoueAkito Hirakata
Oct 11, 2016·Case Reports in Ophthalmological Medicine·Takayuki TsuyamaTomohiro Hattori
Mar 25, 2011·Cutaneous and Ocular Toxicology·Ilias GeorgalasChryssanthi Koutsandrea
Apr 5, 2000·Seminars in Ophthalmology·M KameiH Lewis
Apr 5, 2000·Seminars in Ophthalmology·O Cekic, M Ohji
Jun 3, 2009·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Sumit P ShahSteven D Schwartz
Oct 1, 2003·Clinical & Experimental Ophthalmology·Claire Y Hooper, Robyn H Guymer
Sep 27, 2001·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·W C WuC W Chang
Jan 6, 2004·International Ophthalmology Clinics·J John WooArnold J Kroll
Feb 19, 2005·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Tsung-Tien Wu, Shwu-Jiuan Sheu
Oct 13, 2012·Korean Journal of Ophthalmology : KJO·Ungsoo Samuel KimJoon Haeng Lee
Dec 22, 2006·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Yonina RonDov Weinberger
Jun 1, 1997·Indian Journal of Ophthalmology·T Das
Apr 5, 2000·Seminars in Ophthalmology·D Wong, N Lois
Jun 5, 2001·Current Opinion in Ophthalmology·J L Borrillo, C D Regillo
Sep 8, 2000·Current Opinion in Ophthalmology·M W Johnson
Jul 20, 2002·International Ophthalmology Clinics·Derek B Lauritzen, John J Weiter

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Ophthalmology
Daniel B RothH Lewis
Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
L HesseP Kroll
© 2021 Meta ULC. All rights reserved