Surgical resection for non-familial adenomatous polyposis-related intra-abdominal fibromatosis

The British Journal of Surgery
M J WilkinsonD C Strauss

Abstract

Intra-abdominal fibromatosis (IAF) in the context of familial adenomatosis polyposis (FAP) is associated with significant morbidity and high recurrence rates after surgical resection. Non-surgical treatments are therefore advocated. This study explored outcomes in patients with IAF not associated with FAP who underwent surgical resection. Data were analysed from a prospectively collected database at a sarcoma tertiary referral centre. From 2001 to 2011, 15 patients without FAP underwent primary curative surgical resection of IAF. Their median (range) age was 42 (19-64) years. Median tumour size was 18 (8.5-25) cm and weight 1306 (236-2228) g. Complete macroscopic clearance was obtained in all patients. There were no deaths in hospital or within 30 days and only one patient developed a major complication. Median follow-up was 40 (6-119) months. During follow-up two patients developed a recurrence after a disease-free interval of 12 and 16 months. In contrast to FAP-associated IAF, non-FAP-associated IAF has a very low recurrence rate after surgical resection. Surgical resection is therefore advocated as first-line treatment in patients with non-FAP-associated IAF when resection can be performed with low morbidity.

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Citations

Aug 2, 2013·Diagnostic Pathology·Dongxian JiangXiongzeng Zhu
Mar 8, 2014·Annals of Surgical Oncology·Michelle J WilkinsonDirk C Strauss
Feb 13, 2016·International Journal of Surgery Case Reports·Sala AbdallaAleksandras Uzkalnis
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Feb 23, 2019·Journal of Surgical Case Reports·Jurian Kloeze, Martin van Veen
May 23, 2019·World Journal of Clinical Oncology·Aikaterini MastorakiNikolaos Arkadopoulos

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