Surgical resection of metastases to the adrenal gland: a single center experience

Langenbeck's Archives of Surgery
I HornsteinT J Musholt

Abstract

Only limited data exist on the treatment and outcome of adrenal metastases that derive from different primary tumor entities. Due to the lack of evidence, it is difficult to determine the indication for surgical resection. We assessed the outcome of 45 patients (28 men, 17 women) with adrenal metastases who underwent surgery (1990-2014). The median age at the time of adrenal surgery was 62 years (range 44-77 years). We were able to evaluate follow-up data of 41 patients. Primary tumor types were liver n = 12 (hepatocellular carcinoma n = 9, cholangiocellular carcinoma n = 2, sarcoma n = 1), upper GI tract n = 5 (esophagus n = 2, stomach n = 3), lung n = 9, kidney n = 6, neuroendocrine tumors n = 3, colon n = 2, ovarial n = 2, melanoma n = 2, others n = 4. The overall median survival time was 14 months (95 % CI 8.375-19.625). The survival rates at 1, 2, 5, and 10 years were 60, 31, 21, and 11 %, respectively. There were statistically significant differences in the survival time according to the resection status (R0 vs. R1/R2) (p < 0.001) and the type of the primary tumor (p = 0.009), while the metachronous or synchronous occurrence of adrenal metastases did not affect the prognosis. Resection of adrenal metastases can improve th...Continue Reading

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Citations

Sep 19, 2020·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·J I StaubitzT J Musholt
Feb 12, 2021·The American Surgeon·Iswanto SucandyAlexander Rosemurgy
Sep 13, 2020·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Sorin T AlexandrescuIrinel Popescu
Aug 10, 2021·World Journal of Clinical Cases·Hai-Yi LongBao-Xian Liu

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