Surgical sepsis

Urologia
Gabriele Sganga

Abstract

Sepsis represents a clinical syndrome following an infection and it is characterized by classical signs of systemic inflammatory response syndrome (SIRS): fever or ipothermia, tachycardia, tachipnea, leucocytosis or leucopenia. There may also be symptoms related to a specific infection such as a cough in pneumonia or burning with urination in a kidney infection, and abdominal pain in an intraabdominal sepsis. Common locations for the primary infection include lungs, brain, urinary tract, skin and soft tissues, and mainly abdominal organs. Patients who develop sepsis have an increased risk of complications and death and face higher healthcare costs and longer treatment. The infection is caused most commonly by bacteria, but can also be by fungi, viruses, or parasites. Severe sepsis is sepsis causing poor organ function or insufficient blood flow; septic shock is the situation with ipotension and/or need for high dosage of inotropes or vasopressors and multiple organ failure syndrome is when multiple organ dysfunction or failure is present. Outcomes depend on the severity of disease with the risk of death from sepsis being as high as 30%, severe sepsis as high as 50%, and septic shock as high as 80%. Prevention, early diagnosis, ...Continue Reading

References

Apr 12, 2003·Critical Care Medicine·Mitchell M LevyUNKNOWN SCCM/ESICM/ACCP/ATS/SIS
Feb 14, 2004·Intensive Care Medicine·Simon FinferJohn Myburgh
Aug 18, 2004·Critical Care : the Official Journal of the Critical Care Forum·Aukje van GestelBen A van Hout
Feb 1, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·P PóvoaH Sabino
Aug 6, 2009·Journal of Chemotherapy·V Emmi, G Sganga
Jun 3, 2010·Frontiers in Bioscience (Elite Edition)·Antonino GulloGiuseppe Ristagno
Oct 5, 2012·Clinical Microbiology Reviews·Konrad ReinhartChristiane S Hartog

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Citations

Jul 12, 2017·Mediators of Inflammation·Jingyao ZhangChang Liu

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