Surgical strategies and novel therapies for locally advanced pancreatic cancer

Journal of Surgical Oncology
Jad Abou-Khalil, Flavio G Rocha

Abstract

Many patients with pancreatic cancer are not candidates for surgical resection due to involvement of critical mesenteric vascular structures. We compare and contrast the commonly used classification systems for borderline resectable and locally advanced pancreatic cancer. We describe the current strategies in managing venous and arterial involvement, as well as the role of neoadjuvant chemotherapy and chemoradiation, before explanding on a novel clinical trial in this patient population.

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Citations

Oct 22, 2019·Arquivos De Gastroenterologia·Guilherme Hoverter CallejasEverton Cazzo
Apr 9, 2021·Journal of Surgical Oncology·Marc A AttiyehLaleh G Melstrom
May 25, 2021·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Alex B BlairBradley N Reames

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