Surgical stress response after colorectal resection: a comparison of robotic, laparoscopic, and open surgery

Techniques in Coloproctology
J ShibataT Watanabe

Abstract

The perioperative immune status of colorectal robotic surgery (RS), laparoscopic surgery (LS), and open surgery (OS) patients has not been compared. Our aim was to evaluate perioperative stress and immune response after RS, LS and OS. This prospective study included 46 colorectal surgery patients from the Department of Surgical Oncology of the University of Tokyo Hospital. Peripheral venous blood samples were obtained preoperatively and on postoperative days 1, 3, and 6. We evaluated expression of HLA-DR (marker of immune competence), C-reactive protein (CRP) levels, and lymphocyte subset counts (natural killers, cytotoxic T cells and helper T cells). Fifteen, 23, and 8 patients underwent RS, LS and OS, respectively. HLA-DR expression was the lowest on day 1 and gradually increased on days 3 and 6 in all the groups. There was no significant difference in postoperative HLA-DR expression between the RS and LS group. However, on day 3, HLA-DR expression in the RS group was significantly higher than in the OS group (p = 0.04). On day 1, CRP levels in the LS group were significantly lower than in the RS group (p = 0.038). There were no significant perioperative changes in the lymphocyte subset cell count between the three groups. Pe...Continue Reading

References

Aug 27, 2002·Diseases of the Colon and Rectum·Marco BragaValerio Di Carlo
Mar 14, 2003·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A HartleyJ I Geh
Jul 9, 2003·Diseases of the Colon and Rectum·Matthias W WichmannFriedrich-Wilhelm Schildberg
Nov 8, 2003·Intensive Care Medicine·Sascha FlohéChristian Waydhas
Nov 12, 2003·The Journal of Allergy and Clinical Immunology·Kazushige KawaiHirokazu Nagawa
Oct 1, 2004·Surgical Endoscopy·R VeldkampUNKNOWN European Association of Endoscopic Surgery (EAES)
Jul 20, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David G JayneUNKNOWN UK MRC CLASICC Trial Group
Sep 26, 2007·Annals of Surgery·James FleshmanUNKNOWN Clinical Outcomes of Surgical Therapy Study Group
Feb 21, 2009·Journal of the American College of Surgeons·Joel M BaumgartnerMartin D McCarter
Jun 3, 2009·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·S F KerrR Glynne-Jones
Feb 24, 2010·International Journal of Colorectal Disease·Sang-Ah HanHo-Kyung Chun
Sep 8, 2011·Surgical Endoscopy·Konstantinos E TsimogiannisGeorge Basdanis
Oct 3, 2012·The British Journal of Surgery·J Y ParkJ H Lee
Jan 11, 2013·Diseases of the Colon and Rectum·Rosaria Scarpinata, Emad H Aly
Feb 12, 2013·The Lancet Oncology·Martijn Hgm van der PasUNKNOWN COlorectal cancer Laparoscopic or Open Resection II (COLOR II) Study Group
Mar 13, 2013·Diseases of the Colon and Rectum·Joshua A TylerSean C Glasgow
Apr 9, 2013·World Journal of Surgery·Wissam J HalabiAlessio Pigazzi
Aug 21, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Carrie Y Peterson, Martin R Weiser
Sep 3, 2013·Surgical Endoscopy·Deborah S KellerConor P Delaney
Feb 6, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Chang Woo KimSeung Hyuk Baik
Apr 25, 2014·Gastroenterology Report·Styliani KaranikaGeorge E Theodoropoulos

❮ Previous
Next ❯

Citations

Mar 10, 2016·Surgical Infections·Norman GalbraithHiram C Polk
Oct 11, 2015·World Journal of Surgical Oncology·Nicola de'AngelisFrancesco Brunetti
Jun 11, 2015·International Journal of Clinical Oncology·Soichiro IshiharaToshiaki Watanabe
Jul 16, 2015·Surgical Endoscopy·Joshua A BoysSteven R DeMeester
Nov 7, 2016·International Journal of Colorectal Disease·Marek ZawadzkiWojciech Witkiewicz
Aug 18, 2017·International Journal of Molecular Sciences·Leonard AngkaRebecca C Auer
Sep 28, 2017·Asian Journal of Endoscopic Surgery·Hiroaki Nozawa, Toshiaki Watanabe
Jan 18, 2018·Clinical & Experimental Metastasis·Corina BehrenbruchFrédéric Hollande
Jun 30, 2019·Journal of Clinical Medicine·Malgorzata Krzystek-KorpackaAndrzej Gamian
Jun 25, 2019·Annals of the Royal College of Surgeons of England·L BrownUNKNOWN NoSTRA (Northern Surgical Trainees Reseach Association)
Jun 16, 2018·Scientific Reports·Małgorzata Krzystek-KorpackaAndrzej Gamian
Nov 11, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mariusz G FleszarMałgorzata Krzystek-Korpacka
Feb 10, 2021·Journal of Clinical Medicine·Mariusz G FleszarMałgorzata Krzystek-Korpacka
May 8, 2021·Scientific Reports·Marco MiloneGiovanni Domenico De Palma

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Lower Grade Glioma

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.