Surgical treatment and outcome for node-negative gastric cancer

Surgery
Y MaeharaK Sugimachi

Abstract

The clinicopathologic characteristics and prognosis for patients with node-negative gastric cancer have heretofore remained to be determined. We analyzed data on 730 of our patients with node-negative gastric cancer who underwent curative gastric resection in the Department of Surgery II, Kyushu University Hospital, between 1965 and 1990, with reference to prognostic factors. The presence of lymph node metastasis was determined by means of routine hematoxylin-eosin staining of excised tissues. The 5-year survival rate was 91.7% and the 10-year rate was 88.5%; thus the prognosis was good for patients with node-negative gastric cancer. When the prognosis was analyzed by stratification of each clinicopathologic factor, the survival time was shorter for older patients when the size of the tumor was larger, when the tumor involved the entire stomach, and when-tissues revealed infiltrative growth, serosal invasion, and lymphatic invasion. Extensive lymph node dissection was performed for 86.6% of the patients, and for these patients the prognosis was better, with a statistical difference. In a multivariate analysis, tumor size, serosal invasion, and extensive lymph node dissection proved to be independent prognostic factors for patie...Continue Reading

References

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Citations

Apr 11, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Xiaowen LiuYanong Wang
Dec 25, 2010·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Miao-zhen QiuRui-hua Xu
Dec 24, 2002·Journal of the American College of Surgeons·Yasuhiro KoderaAkimasa Nakao
Jun 11, 2003·Annals of Surgery·David A KoobyMartin S Karpeh
Jul 5, 2007·Journal of Gastroenterology and Hepatology·Chin-Chun LeeWing-Yiu Lui
May 27, 2009·Journal of Gastroenterology and Hepatology·Kuo-Hung HuangWin-Yiu Lui
May 11, 2011·World Journal of Surgical Oncology·Ramakrishnan A SeshadriRama Ranganathan
Mar 3, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J-H ChenW-Y Lui
May 29, 2009·Journal of Surgical Oncology·Daisuke IchikawaEigo Otsuji
May 13, 2010·Journal of Surgical Oncology·Hiroaki SaitoMasahide Ikeguchi
Nov 15, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·I S LeeB S Kim
Sep 2, 1998·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G R Jatzko, P H Lisborg
Feb 27, 2001·Journal of Surgical Oncology·W Lawrence
Sep 14, 2021·Frontiers in Oncology·Jiao-Bao HuangPing Li

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