Surgical treatment by electrical stimulation of the auditory cortex for intractable tinnitus

Brain Stimulation
C Fabien LitréPhilippe Peruzzi

Abstract

Tinnitus is a public health issue in France. Around 1% of the population is affected and 30,000 people are handicapped in their daily life. The treatments available for disabling tinnitus have until now been disappointing. We are reporting on the surgical treatment by electrical stimulation of the auditory cortex of a female patient affected by disabling tinnitus that resisted classical treatments. The tinnitus appeared suddenly 10 years ago after a left ear tympanoplasty. The acouphenometry measures revealed a bilateral tinnitus, predominant on the right side, constant, with high frequency (6000 Hz). Transcranial magnetic stimulation (TMS) was performed at first with several supraliminal and infraliminal protocols. This showed promising results. Anatomic and functional magnetic resonance imaging (fMRI) of the auditory cortex before and after repetitive TMS (rTMS) demonstrated a modification of the cortical activity and where the ideal location for a cortical electrode might be, to straddle primary and secondary auditory cortex. After these investigations, two quadra polar electrodes (Resume, Medtronic Ltd, Hertfordshire, UK), connected to a stimulating device implanted under the skin (Synergy, Medtronic Ltd), were extradurally...Continue Reading

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Citations

Nov 22, 2013·Neuromodulation : Journal of the International Neuromodulation Society·Dirk De RidderMichael P Kilgard
Dec 3, 2014·Brain Stimulation·Dirk De Ridder, Sven Vanneste
Sep 17, 2019·Neuromodulation : Journal of the International Neuromodulation Society·Ann N DeklerckIngeborg J M Dhooge
Apr 4, 2017·Neuromodulation : Journal of the International Neuromodulation Society·Dirk De RidderSven Vanneste
Sep 10, 2010·Current Opinion in Otolaryngology & Head and Neck Surgery

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