Surgical treatment for mesial temporal lobe epilepsy associated with hippocampal sclerosis

Revue neurologique
B MathonS Clemenceau

Abstract

Hippocampal sclerosis is the most common cause of pharmacoresistant epilepsy amenable for surgical treatment and seizure control. The aim of this article is to review and evaluate the published literature related to the outcome of the surgical treatment of mesial temporal lobe epilepsy (MTLE) associated with hippocampal sclerosis (HS) and to describe the future prospects in this field. Surgery of MTLE associated with HS achieves long-term seizure freedom in about 70% (62-83%) of cases. Seizure outcome is similar in the pediatric population. Mortality following temporal resection is very rare (<1%) and the rate of definitive neurological complication is low (1%). Gamma knife stereotactic radiosurgery used as a treatment for MTLE would have a slightly worse outcome to that of surgical resection, but would provide neuropsychological advantage. However, the average latency before reducing or stopping seizures is at least 9 months with radiosurgery. Regarding palliative surgery, amygdalohippocampal stimulation has been demonstrated to improve the control of epilepsy in carefully selected patients with intractable MTLE who are not candidates for resective surgery. Recent progress in the field of imaging and image-guidance should allo...Continue Reading

References

Jul 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·C J Mace, M R Trimble
Jun 1, 1988·Annals of Neurology·B P Hermann, A R Wyler
Oct 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·N D KitchenD G Thomas
Nov 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·A S NaylorC Kruse-Larsen
Feb 1, 1993·Journal of Neuroimmunology·R S DeviK Prabhakaran
Jan 1, 1996·Stereotactic and Functional Neurosurgery·C J Whang, Y Kwon
May 1, 1997·International Journal of Radiation Oncology, Biology, Physics·G GlosserM M Urie
Dec 24, 1997·Neuroradiology·S LehéricyM Baulac
May 23, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·H A RingM R Trimble
Nov 18, 1998·Annals of Neurology·E WyllieP Ruggieri
Jul 13, 1999·Annals of Neurology·M R SperlingM J O'Connor
Jan 10, 2002·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·T LoddenkemperH O Lüders
Jan 10, 2002·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·I OsorioS B Wilkinson
Oct 29, 2002·Annals of Neurology·Kristl VonckJacques Caemaert
Nov 13, 2002·Neurology·C ChristodoulouB K Toone
Nov 27, 2002·Journal of Neurosurgery·Hans ClusmannChristian E Elger
Nov 27, 2002·Neurology·R G JarrarE Laws
Mar 13, 2003·Mayo Clinic Proceedings·Jeffrey R Buchhalter, Randa G Jarrar
Mar 21, 2003·Pediatric Neurosurgery·D Barry SinclairW Colmers
Apr 15, 2003·Journal of Neurosurgery·H Gregor WieserYasuhiro Yonekawa

❮ Previous
Next ❯

Citations

Feb 8, 2016·Acta neurochirurgica·Bertrand Mathon, Stéphane Clemenceau
May 14, 2016·Epilepsy & Behavior : E&B·S M Jessica BehWendyl J D'Souza
Oct 25, 2016·International Journal of Surgery·Dattatraya MuzumdarUrvashi Shah
Dec 31, 2016·World Neurosurgery·Ali A Asadi-PooyaAshwini Sharan
Apr 9, 2017·World Neurosurgery·Bertrand MathonStéphane Clemenceau
Feb 16, 2018·Current Neurology and Neuroscience Reports·Sonal Bhatia, Sarah E Schmitt
Sep 19, 2017·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Bowen Chang, Jiwen Xu
Feb 12, 2017·Der Nervenarzt·C HoppeC E Elger
Feb 6, 2020·Journal of Lasers in Medical Sciences·Ensieh KhalkhalZahra Akbari
Jul 9, 2020·Journal of Central Nervous System Disease·Boulenouar MesraouaAli A Asadi-Pooya
Aug 28, 2020·The Journal of International Medical Research·Yongsu ZhengZucai Xu
Feb 25, 2017·Current Opinion in Neurology·Marianna Spatola, Josep Dalmau
Jan 4, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ali A Asadi-PooyaAmir Savardashtaki
Sep 3, 2019·Neuropharmacology·Theresa AuerChristoph Schwarzer
Oct 24, 2020·Annales de pathologie·Suzanne TranFranck Bielle
Jul 22, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Fatme Seval IsmailUwe Schlegel

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.