Surgical treatment of acute limb ischaemia in the presence of malignancy

International Journal of Surgery
Gareth Morris-Stiff, Michael H Lewis

Abstract

The aim of this study was to examine the outcome of surgical treatment of acute limb ischaemia (ALI) developing in the presence of malignancy. Patients undergoing emergency surgery were identified from theatre registers, notes were reviewed, and data collected in relation to indications for, and outcome following operation. All patients with a current or past medical history of histologically confirmed malignant disease were identified and their notes specifically reviewed to determine the staging of their tumours. The results of the malignancy cohort were compared to a group of patients undergoing surgery for ALI of other aetiologies. Fourteen patients with a malignancy were identified with ALI and in addition there were 102 without malignancy. The cohort with a malignancy contained a higher proportion of males (p=0.0305), and a greater number of smokers (p=0.037) than those with other aetiologies for ALI. The peri-operative management of the 2 groups was similar. Histological examination revealed tumour thrombus in only 1 case. The recurrence (29% versus 18%; p=0.328) and amputation rates (29% versus 17%; p=0.278) were similar, however, the 30-day (50% versus 30%; p=0.038) and 60-day mortality rates (100% versus 35%; p<0.001)...Continue Reading

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Citations

Jun 1, 2012·Journal of Foot and Ankle Research·Peter A LazzariniSuzanne S Kuys
Sep 20, 2015·Journal of Vascular Surgery·Chalotte Winther NicolajsenNikolaj Eldrup
May 23, 2014·Vascular·Daniel SilverbergMoshe Halak
Feb 18, 2014·Vascular Medicine·Elie MouhayarTam Huynh
May 16, 2012·British Journal of Hospital Medicine·Jolene WitherspoonMichael Lewis
Nov 30, 2018·ANZ Journal of Surgery·Harkant SinghAjay Savlania
Jan 4, 2020·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Martin BjörckKumud Rai
Apr 28, 2021·Journal of Vascular Surgery·Nicholas GovsyeyevMark Nehler

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