PMID: 8956893Dec 1, 1996Paper

Surgical treatment of epilepsy: the problem of lesion/focus incongruence

Surgical Neurology
D B ClarkeD Fish

Abstract

This study suggests an alternative surgical strategy for treating patients with intractable epilepsy in whom a lesion, visualized by imaging, is found to be at a distance from the maximal electroencephalographic abnormality (focus). Sixty patients (divided into three groups of 20), all of whom have had surgical resection for intractable epilepsy, are reviewed. Group A patients, representing the most common situation of a congruent electroencephalographic focus and structural lesion, underwent resection of the lesion/focus. Group B patients, in whom the focus and the lesion are incongruent, underwent resection of the focus only. Group C patients are those where the focus and lesion are incongruent; in this group, the lesion only was resected. Group A patients underwent resection of the lesion/focus (sites: 13 temporal, six frontal, and one parietal) with excellent results. Group B patients, in whom the focus only was resected (lesion sites: 14 temporal, four parietal, and two occipital) obtained poor results. Group C patients had excellent results following resection of the lesion only (lesion sites: 12 temporal, seven frontal, and one parietal). The superior surgical outcome in seizure control of group C is comparable to that s...Continue Reading

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Citations

Aug 28, 1999·Journal of the Neurological Sciences·R L Kutsy
Feb 26, 1998·Epilepsy Research·B E SwartzM H Kaufman
Mar 10, 2000·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·E L SoB P Mullan
Nov 21, 2002·Mayo Clinic Proceedings·Elson L So
Apr 29, 1998·Current Opinion in Neurology·W Boling, A Olivier
Jun 1, 2000·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·D B MacDonald, N Pillay

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