Surgical treatment of esophageal cancer in the era of multimodality management

Annals of the New York Academy of Sciences
Alicia S BorggreveLucas Goense

Abstract

Over the last decades, the treatment of resectable esophageal cancer has evolved into a multidisciplinary process in which all players are essential for treatment to be successful. Medical oncologists and radiation oncologists have been increasingly involved since the implementation of neoadjuvant therapy, which has been shown to improve survival. Although esophagectomy is still considered the cornerstone of curative treatment for locally advanced esophageal cancer, it remains associated with considerable postoperative morbidity, despite promising results of minimally invasive techniques. In this light, both physical status and response to neoadjuvant therapy may be important factors for selecting patients who will benefit from surgery. Furthermore, it is important to optimize the entire perioperative trajectory: from the initial outpatient clinic visit to postoperative discharge. Enhanced recovery after surgery is increasingly recognized for esophagectomy and emphasizes perioperative aspects, such as nutrition, physiotherapy, and pain management. To date, several facets of esophageal cancer treatment remain topics of debate, such as the preferred neoadjuvant treatment, anastomotic technique, extent of lymphadenectomy, organiza...Continue Reading

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Citations

Jul 28, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Han TangJun Yin
Feb 23, 2020·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Kelly R HaisleyChristy M Dunst
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Feb 8, 2021·Journal of the American College of Surgeons·W Peter SawyerJohn S Bolton
Apr 20, 2021·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Flavio Roberto TakedaIvan Cecconello
Apr 23, 2021·Cancer Biotherapy & Radiopharmaceuticals·Weihe ZhouYi Jiang
Apr 23, 2021·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Li-Xiang MeiMing-Wu Chen
Apr 18, 2021·The Journal of Surgical Research·Huan-Ni LiLi-Xiang Mei

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