Surgical treatment of extravasation injuries: experience of the Hospital das Clínicas, Faculty of Medicine, University of São Paulo

Revista do Colégio Brasileiro de Cirurgiões
Dimas André MilcheskiRolf Gemperli

Abstract

to report the experience of the Division of Plastic Surgery of the Hospital das Clínicas of the Medical School of the University of São Paulo in the treatment of cutaneous lesions due to accidental extravasation of drugs. we included patients with lesions due to extravasation of drugs over a period of 18 months. We retrospectively evaluated the following parameters: age, diagnoses during hospitalization and comorbidities, serum levels of albumin and hemoglobin, place of hospitalization, drug involved, anatomic segment affected, therapeutic management and death during hospitalization. we followed-up 14 patients. The main drug involved was noradrenaline (21%). All patients underwent debridement of tissue necrosis. Three patients were submitted to flaps after preparation of the wound bed with negative pressure therapy, with good results. Seven patients had no definitive treatment of their lesions due to lack of clinical conditions. in patients with favorable clinical conditions, the definitive treatment with flaps was adequate for cases of wounds due to extravasation of drugs in the subcutaneous tissue when there was exposure of noble structures.

References

Jun 2, 1998·The Annals of Pharmacotherapy·J L Chen, M O'Shea
Aug 17, 2000·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·E Kassner
May 21, 2004·Annals of Oncology : Official Journal of the European Society for Medical Oncology·R A EnerM Styler
Oct 27, 2004·Paediatric Anaesthesia·Alexander L Garden, Peter C Laussen
Oct 30, 2004·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·Francesco D'AndreaNicolò Scuderi
Aug 27, 2005·Journal of Surgical Oncology·Pietro NapoliFrancesco Moschella
Dec 7, 2006·Oncology Nursing Forum·Rita WickhamDominick Corbi
May 9, 2007·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·Philipp FallscheerClaudia Meuli-Simmen
Apr 21, 2009·Anesthesia and Analgesia·Sanjay M BhanankerKaren B Domino
Jan 25, 2011·Seminars in Oncology Nursing·Lisa Schulmeister
Nov 30, 2011·The Journal of Hand Surgery·Michael G Hannon, Steve K Lee
Nov 30, 2012·Journal of Plastic Surgery and Hand Surgery·Cemal FıratAhmet Hamdi Aytekin
Jun 6, 2013·ISRN Dermatology·S Al-BennaJ Holley
Jan 10, 2014·The Journal of Hand Surgery, European Volume·I GoutosH Giele
Jan 15, 2014·Pharmacotherapy·Paul M ReynoldsTyree H Kiser
Apr 10, 2014·The Annals of Pharmacotherapy·Ann Le, Samit Patel
Feb 26, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·J BoulangerUNKNOWN Comité de l’évolution des pratiques en oncologie (CEPO)
Aug 25, 2016·Plastic and Reconstructive Surgery·Ersilia L Anghel, Paul J Kim

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.