PMID: 7027965Sep 1, 1981Paper

Surgical treatment of familial benign chronic pemphigus

Archives of Dermatology
C P CrottyR K Winkelmann

Abstract

Familial benign chronic pemphigus (Hailey and Hailey disease) is a rare, recalcitrant, often disabling genodermatosis that may not respond to conservative dermatologic therapy. We describe herein five patients with intertriginous familial benign chronic pemphigus who underwent excision and split-thickness skin grafting. All were men whose duration of disease ranged from one to 38 years. Follow-up evaluations ranging from ten months to nine years revealed no recurrence in graft sites in three patients, mild recurrence in one patient after eight years, and one death from pulmonary embolus in the postoperative period. The occurrence of familial benign chronic pemphigus around graft edges was a universal, but relatively minor, problem. Surgical excision provided definite relief from an otherwise disabling disease in four of our patients and a satisfactory improvement in life-style.

Citations

Nov 1, 1987·British Journal of Plastic Surgery·P MenzS Connolly
Jul 1, 1982·Journal of the American Academy of Dermatology·R J Coskey
Sep 6, 2015·International Journal of Dermatology·Phillip C HochwaltChristian L Baum
Nov 1, 1987·The Journal of Dermatologic Surgery and Oncology·P C DonM O Hassan
Nov 25, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·L A Falto-AizpuruaK Nouri
Jun 1, 1994·The Journal of Dermatology·V N Sehgal, S Jain
Oct 18, 2016·Journal of the American Academy of Dermatology·Benjamin FarahnikDirk M Elston
Oct 9, 2019·American Journal of Clinical Dermatology·Imene Ben LaghaAmor Khachemoune

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