Surgical treatment of intracaval tumor relapse after radical tumor nephrectomy in locally advanced renal cell carcinoma

Der Urologe. Ausg. A
T von ZehmenA Heidenreich

Abstract

About 4-10% of patients with renal cell carcinoma (RCC) demonstrate intracaval tumor thrombi at the time of diagnosis. Furthermore, 2-3% of patients might develop local relapses of which intracaval recurrences represent a rare event with fewer than 15 cases reported in the literature. We report the diagnosis, surgical technique, perioperative complications, and oncological outcome in an additional 6 cases. Between 2008 and 2019, 6 patients were treated with isolated intracaval relapse of RCC. All patients had undergone radical nephrectomy with thrombectomy in the past. The mean time between first surgery and relapse was 45.2 (6-114) months and the mean age of patients was 75 (70-80) years: 2, 3 and 1 patient demonstrated thrombus level II, III, and IV, respectively. A thoracoabdominal and a transperitoneal surgical approach was chosen in 4 and 2 patients, respectively. Perioperative complications were reported according to the Clavien-Dindo classification. Relapse-free, cancer-specific and overall survival were calculated with the Kaplan-Meier method. The cava thrombus could be resected completely in all cases. The mean time of surgery was 330 (260-510) min and the mean blood loss was 1500 (300-6500) ml. Clavien-Dindo grade II ...Continue Reading

References

Apr 1, 1981·The Journal of Urology·R B Smith
Mar 29, 2002·Urologia Internationalis·Michael P FinkelsteinMuhammad S Choudhury
May 17, 2003·The International Journal of Cardiovascular Imaging·Vassiliadis IoannisFilipidis Theodoros
Mar 19, 2004·International Journal of Urology : Official Journal of the Japanese Urological Association·Andrea MinerviniRiccardo Minervini
Feb 18, 2014·International Journal of Urology : Official Journal of the Japanese Urological Association·Ahmed BenkiraneLaurent Zini
Jan 27, 2015·European Urology·Borje LjungbergAxel Bex
Mar 8, 2017·The Journal of Urology·E Jason AbelJose A Karam
May 5, 2018·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Lisa C AdamsMarcus R Makowski
Dec 6, 2018·Der Urologe. Ausg. A·Marc-Oliver Grimm
Feb 6, 2020·Aktuelle Urologie·Peter AlbersSeyed Aharinejad
Feb 13, 2020·Der Urologe. Ausg. A·C DoehnT Steiner

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