Surgical treatment of invasive squamous cell carcinoma of the penis: Brazilian National Cancer Institute long-term experience

Journal of Surgical Oncology
Antônio Augusto OrnellasRaul Quirino

Abstract

We reviewed our long-term experience with surgical treatment of patients with penile carcinoma. From 1960 to 2006, 688 patients with penile carcinoma underwent surgical treatment at our Institute. Several forms of surgical treatment were compared and follow-up data analyzed. Stage stratification demonstrated a better survival rate for patients with stages T1N0 and T1N1,T2N0-1. Patients with well differentiated carcinoma had a higher survival rate than those with moderately and poorly differentiated carcinoma (P < 0.0001 and P = 0.006). Risk stratification showed a better survival rate for patients in the low-risk group (T1G1,T1G2) (P = 0.013 and P < 0.00001). Patients in the intermediate group (T2G1,T2G2,T3G1,T3G2) presented a higher survival rate than patients in the high-risk group (T1-3G3,T4G1-3) (P < 0.00001). Patients who underwent immediate lymphadenectomy had a better survival rate than those who underwent delayed lymphadenectomy (P = 0.002). Stage and tumor grade affected the prognosis of the disease. The presence and the extent of metastasis to the inguinal region were the most important prognostic factors for survival in our patients. Immediate lymphadenectomy is indicated in all patients. Since recurrences were noted...Continue Reading

References

May 1, 1991·British Journal of Urology·A G MaicheM Karkinen
Dec 1, 1991·Urology·M J YoungW B Waters
Aug 1, 1991·The Journal of Urology·A A OrnellasJ R de Moraes
May 1, 1987·The Journal of Urology·V SrinivasW F Whitmore
Apr 1, 1985·Cancer·E E FraleyP H Lange
Sep 1, 1973·The Journal of Urology·F C DerrickW J Yarbrough
Aug 1, 1973·Urology·J H KossowP A Morales
May 1, 1973·Urology·D E JohnsonA G Ayala
Oct 1, 1968·The Journal of Urology·J A Thomas, C S Small
Jul 1, 1984·Urology·C R ReddyS Pratap
Mar 1, 1993·The Journal of Urology·S HorenblasE W van Waardenburg
Aug 1, 1997·British Journal of Urology·C F HeynsD J van Velden
Feb 1, 1964·The Journal of Urology·J H BEGGS, J S SPRATT
Mar 1, 1955·Cancer·W J STAUBITZO J OBERKIRCHER
Sep 1, 1962·Archives of Surgery·M RIVEROS, R GOROSTIAGA
Apr 14, 2005·European Urology·Bin K KroonOmgo E Nieweg

❮ Previous
Next ❯

Citations

Jun 1, 2011·World Journal of Urology·T J NirmalNitin S Kekre
Dec 17, 2008·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·Y NeuzilletT Lebret
Jan 8, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G SonpavdeG Di Lorenzo
Aug 27, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H Van PoppelUNKNOWN ESMO Guidelines Working Group
Nov 21, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kimberly L BradyMarc D Brown
Nov 19, 2009·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Oliver J KayesGareth H Williams
Sep 15, 2010·Annals of Surgical Oncology·Rodolphe ThuretPierre I Karakiewicz
Feb 1, 2014·Asian Journal of Andrology·Jin-You WangDing-Wei Ye
Feb 19, 2014·Virchows Archiv : an International Journal of Pathology·Ch KakiesCh Protzel
Aug 27, 2014·Der Urologe. Ausg. A·O W Hakenberg, C Protzel
May 6, 2014·Magnetic Resonance Imaging Clinics of North America·Sumit Gupta, Arumugam Rajesh
Nov 2, 2015·The Kaohsiung Journal of Medical Sciences·Jiun-Hung GengChao-Yuan Huang
Feb 26, 2013·Actas urologicas españolas·P RomanelliM Tobias-Machado
Oct 31, 2012·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Robert TauberTobias Maurer
Aug 1, 2012·Seminars in Oncology Nursing·Jeanne Held-Warmkessel
Nov 3, 2011·The Urologic Clinics of North America·Steve K Williams, Farhang Rabbani
Nov 3, 2011·The Urologic Clinics of North America·Simon Horenblas
Jun 28, 2011·The Journal of Urology·Kevin N FranksAnne E Kiltie
Jan 18, 2011·The Journal of Urology·Jack H Mydlo
Aug 3, 2010·The Urologic Clinics of North America·P K HegartyC A Pettaway
Aug 19, 2010·Urology·Eduardo SolsonaNick A Watkin
Aug 19, 2010·Urology·Chris F HeynsHendrik van Poppel
Aug 19, 2010·Urology·Vincenzo FicarraMarcos Tobias-Machado
Aug 3, 2010·The Urologic Clinics of North America·Vitaly Margulis, Arthur I Sagalowsky
Feb 19, 2010·European Urology·Giorgio PizzocaroUNKNOWN European Association of Urology (EAU) Guidelines Group on Penile Cancer
Nov 3, 2009·Urologic Oncology·Roberto SalvioniNicola Nicolai
Oct 20, 2009·The Journal of Urology·Robert S SvatekCurtis A Pettaway
Mar 2, 2011·Cancer·Rodolphe ThuretPierre I Karakiewicz
Mar 27, 2010·International Journal of Cancer. Journal International Du Cancer·Niels M GraaflandSimon Horenblas
Oct 26, 2011·BJU International·Samuel DeemStephen Savage
Oct 13, 2012·BJU International·Rodolphe ThuretPierre I Karakiewicz
Oct 13, 2009·BJU International·Niels M GraaflandSimon Horenblas
Mar 24, 2016·Nature Reviews. Urology·Arthur L Burnett
Jun 17, 2015·Current Problems in Cancer·Simon RodneyAsif Muneer

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.