Surgical treatment of primary soft tissue sarcomas involving the chest: experiences in 25 patients

The Thoracic and Cardiovascular Surgeon
J PfannschmidtH Hoffmann

Abstract

Primary soft tissue sarcomas of the chest wall are uncommon and data concerning treatment and results are sparse. We reviewed our experience with chest wall resections of these lesions. Retrospective review of our database identified 25 patients (12 men, 13 women) who underwent chest wall resection for primary soft tissue sarcoma during the 18-year study period (January 1984 through to January 2002). The mean follow-up period was 46.5 months. The 30-day mortality was zero. The cumulative 5-year survival rate of all 25 patients was 56.9 %, and the median survival 99.5 months. This compared with 42.2 % and a median survival of 36.0 months after chest wall resection for high grade tumor histology. Histological type grading clearly influenced long-term survival ( P = 0.036). Local recurrence occurred in 9 patients, 6 of 8 who were resected with positive margins and 3 of 17 who were resected with negative margins. Chest wall resections extended with lung resections did not significantly impair postoperative pulmonary function compared to patients without concomitant lung resections. Chest wall resections in primary soft tissue sarcomas can be accomplished safely with a low mortality rate. Long-term survival can be achieved for prima...Continue Reading

Citations

Mar 7, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Jean-Philippe BerthetCharles-Henri Marty-Ané
May 4, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Dominique FabrePhilippe G Dartevelle
Aug 13, 2009·Annals of Surgical Oncology·Carmen C van der PolTitia E Lans
Sep 22, 2010·World Journal of Surgery·Albertus N van GeelCornelis Verhoef
Feb 7, 2012·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Puja KachrooJay M Lee
Jun 3, 2009·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Satoshi TsukushiNaoki Ishiguro
Sep 17, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Michael W WoutersHouke M Klomp
Jun 12, 2018·Plastic and Reconstructive Surgery·Juho T K Salo, Erkki J Tukiainen
Sep 20, 2019·Journal of Surgical Oncology·Naoya NakahashiToshihiko Yamashita
Apr 9, 2019·International Journal of Surgical Oncology·Tine Rytter SoerensenThomas Baad-Hansen

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