Surgical Treatment of Pulmonary Complications in Behçet's Syndrome

Seminars in Thoracic and Cardiovascular Surgery
H TüzünV Hamuryudan

Abstract

We described disease characteristics, management and outcome of a group of Behçet's syndrome (BS) patients who underwent pulmonary lobectomy, segmentectomy or various pleura interventions for complications due to pulmonary artery or descending aorta involvement. There were 9 patients with BS (8 M/1 F; mean age: 24.8 ± 7.5 and mean disease duration: 4.3 ± 3.8 years) who underwent lung surgery from 2000 to 2017. Their medical files including operation details and radiological and pathological studies were reviewed retrospectively. Lobectomy was done in 6 patients, decortications and pleura interventions in the remaining 3. The reason for the surgical procedures were giant pulmonary arterial aneurysms refractory to the medical treatment (n = 4), pneumothorax due to large cavities (n = 2), pleural effusions refractory to the medical treatment (n = 1), a bronchopleural fistula after embolization (n = 1) and bronchiectasis (n = 1). All patients received medical treatment with cyclophosphamide and corticosteroids before the surgical interventions. The histological examination in patients with pseudo-aneurysms showed destruction of medial elastic fibers, inflammatory cell infiltration of adventitial tissues and penetration into the adj...Continue Reading

Citations

Jun 24, 2019·European Heart Journal Cardiovascular Imaging·Leyla Elif Sade, Ali Akdogan
Mar 13, 2020·Interactive Cardiovascular and Thoracic Surgery·Xiaobing LiRufang Zhang
Jan 27, 2019·Internal and Emergency Medicine·Sinem Nihal Esatoglu, Gulen Hatemi
Nov 21, 2020·Curēus·Dwayne M Hansen, Cornelius Dyke
Jul 30, 2021·Journal of Inflammation Research·Yesim OzgulerGulen Hatemi

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