Thirty-nine patients (mean age: 33 years) with Takayasu's disease were observed over the past 8 years. Among these patients, 33 had surgical intervention with a mean follow-up of 4 years. Lesions of the aortic arch were the most common (29 patients, 69 lesions) and frequently were associated with lesions in another site as well. However, in this group of patients, the infrequent presence of signs of cerebral vascular insufficiency limited the number of suitable surgical candidates to 14 patients. Lesions of the renal arteries were noted in 25 patients (37 lesions) and were associated with coarctation of the thoracoabdominal aorta in 12 patients. In contrast to lesions of the aortic arch, the presence of severe hypertension was a frequent indication for surgery in Takayasu's disease. Twenty-one patients had operation. Twenty of 21 patients were considered cured or improved of hypertension. The one patient who received no benefit was the only operative death of the study. In conclusion, although Takayasu's disease is progressive and the life expectancy is foreshortened, hypertension secondary to aortic and renal artery lesions is a frequent and important indication for aggressive operative treatment.
Takayasu arteritis: utility and limitations of magnetic resonance imaging in diagnosis and treatment
Quality of life in patients with Takayasu's arteritis is impaired and comparable with rheumatoid arthritis and ankylosing spondylitis patients
The clinical application of 'edema-weighted' magnetic resonance imaging in the assessment of Takayasu's arteritis
Middle aortic syndrome: distal thoracic and abdominal coarctation, a disorder with multiple etiologies
Graft patency evaluation with colour-Doppler ultrasonography after bypass surgery in Takayasu's arteritis: a direct colour-flow lumen imaging method
Takayasu arteritis in France: a single-center retrospective study of 82 cases comparing white, North African, and black patients
Arterial wall thickness measurements by B mode ultrasonography in patients with Takayasu's arteritis
Ghrelin and adipokines as circulating markers of disease activity in patients with Takayasu arteritis
Takayasu arteritis: intravascular contrast medium for MR angiography in the evaluation of disease activity
Markers of endothelial damage and repair in Takayasu arteritis: are they associated with disease activity?
Radionuclide renography predicts functional changes in patients with renal artery involvement by Takayasu's arteritis
Takayasu's arteritis and fibromuscular dysplasia as causes of acquired atypical coarctation of the aorta: retrospective analysis of seven cases
The role of (18) F-fluorodeoxyglucose-positron emission tomography in the assessment of disease activity in patients with takayasu arteritis
Detecting disease extent and activity of Takayasu arteritis using whole-body magnetic resonance angiography and vessel wall imaging as a 1-stop solution
Is (18)F-fluorodeoxyglucose positron emission tomography scanning a reliable way to assess disease activity in Takayasu arteritis?
Takayasu's arteritis and congenital coarctation of the descending thoracic and abdominal aorta: a critical review
Captopril-induced functional renal insufficiency in patients with bilateral renal-artery stenoses or renal-artery stenosis in a solitary kidney
Aortic coarctation is a congenital condition characterized by narrowing of the aorta. Discover the latest research on this disease here.