Surgical treatment of thymoma: an 11-year experience with 761 patients

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Yang ZhaoHeng Zhao

Abstract

Thymomas are rare, and information regarding their surgical outcomes and possible prognostic factors is limited. In this study, we aimed to determine the clinicopathological characteristics of thymoma and estimate independent predictors of both overall and disease-free survival in thymoma patients. We carried out a retrospective review of the clinicopathological characteristics and prognostic factors in 761 consecutive patients with pathologically confirmed thymoma treated in Shanghai Chest Hospital between January 2001 and December 2011. Survival was calculated using the Kaplan-Meier method and evaluated with log-rank tests. Multivariable analysis was performed using the Cox regression model. Complete follow-up information was available for 544 patients. The overall survival rate was 92.8% at 5 years and 90.5% at 10 years. The 5- and 10-year disease-free survival was 87.9 and 82.1%, respectively. On multiple Cox regression analysis, the Masaoka-Koga clinical stage [odds ratio (OR), 2.057; 95% confidence interval (CI), 1.454-2.911; P < 0.01] and sex (OR, 2.244; 95% CI, 1.115-4.519; P = 0.02) were found to be independent predictors of overall survival. The Masaoka-Koga clinical stage (OR, 2.127; 95% CI, 1.487-3.042; P < 0.01) an...Continue Reading

References

Apr 12, 2002·International Journal of Cancer. Journal International Du Cancer·Ralf J RiekerHerwart F Otto
Dec 3, 2002·The American Journal of Surgical Pathology·Lara ChalabreysseFrançoise Thivolet-Bejui
Sep 10, 2003·The Annals of Thoracic Surgery·Kazuya Kondo, Yasumasa Monden
Apr 6, 2004·The Annals of Thoracic Surgery·Kazuya KondoYasumasa Monden
May 30, 2006·The Annals of Thoracic Surgery·Frank C Detterbeck
Oct 5, 2010·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Eric A Engels
Oct 21, 2010·American Journal of Clinical Pathology·Cesar A MoranSaul Suster
Aug 24, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·James HuangPatrick J Loehrer
Oct 4, 2011·The Annals of Thoracic Surgery·Benny WekslerArjun Pennathur
Nov 26, 2011·The Annals of Thoracic Surgery·Matthew J BottJames Huang
Jun 16, 2012·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Mi Kyung BaeKyung Young Chung
Nov 13, 2013·Seminars in Thoracic and Cardiovascular Surgery·Usman Ahmad, James Huang

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Citations

Mar 29, 2019·Journal of Surgical Oncology·Jae Kwang YunUNKNOWN other members of the Korean Association for Research on the Thymus (KART).
Nov 7, 2019·Journal of Clinical Medicine·Rumi HiguchiMasao Omata
Sep 8, 2017·Journal of Medical Case Reports·Yuto KatoRyuji Nohara
Aug 8, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Sara Victoria SolderaGeoffrey Liu
May 17, 2017·Chinese Journal of Cancer·Zu-Yang YuanJie He
May 6, 2017·Experimental Hematology & Oncology·Yusuke IsshikiYukihiro Yoshida
Mar 8, 2021·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·C XuJ Wang
Jan 31, 2021·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Yudai TateishiTakeshi Kaneko
Dec 15, 2020·Oncology Research and Treatment·Haibo MouLanfang Yu

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